13C C16 Sphingomyelin (d18:1/16:0)
- Product Name
- 13C C16 Sphingomyelin (d18:1/16:0)
- CAS No.
- 144236-99-7
- Chemical Name
- 13C C16 Sphingomyelin (d18:1/16:0)
- Synonyms
- 13C C16 Sphingomyelin (d18:1/16:0);C16 Sphingomyelin-13C (d18:1/16:0-13C);R-[R*,S*-(E)]]-4-hydroxy-7-(1-hydroxy-2-hexadecenyl)-N,N,N-trimethyl-9-oxo-3,5-dioxa-8-aza-4-phosphatetracosan-1-aminium-9-13C,4-oxide,innersalt
- CBNumber
- CB74665763
- Molecular Formula
- C39H79N2O6P
- Formula Weight
- 704.037121
- MOL File
- 144236-99-7.mol
13C C16 Sphingomyelin (d18:1/16:0) Property
- storage temp.
- Store at -20°C
- solubility
- Chloroform: soluble; Ethanol: soluble; Methanol: soluble
- form
- A solid
N-Bromosuccinimide Price
- Product number
- 24452
- Product name
- 13C C16 Sphingomyelin (d18:1/16:0)
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $317
- Updated
- 2024/03/01
- Product number
- 1507EN
- Product name
- [(E,2S,3R)-2-((113C)Hexadecanoylamino)-3-hydroxyoctadec-4-enyl]2-(trimethylazaniumyl)ethylphosphate
- Packaging
- 1mg
- Price
- $525
- Updated
- 2021/12/16
13C C16 Sphingomyelin (d18:1/16:0) Chemical Properties,Usage,Production
Description
C16 Sphingomyelin-13C (d18:1/16:0-13C) is intended for use as an internal standard for the quantification of C16sphingomyelin by GC- or LC-MS. C16 Sphingomyelin is a naturally occurring sphingolipid. Levels of C16 sphingomyelin are elevated in the prefrontal cortex and cerebellum in a rat model of diabetes induced by streptozotocin (STZ; ), as well as in the liver in mouse models of Niemann-Pick type C1 disease. Plasma levels of C16 sphingomyelin are decreased in patients with prostate cancer. Model membranes containing C16 sphingomyelin, 1-palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC; ), and cholesterol have been used in the study of lipid raft dynamics and membrane organization. [Matreya, LLC. Catalog No. 2200]
Uses
N-Palmitoyl-D-sphingomyelin-13C is a deuterated labeled N-Palmitoyl-D-sphingomyelin[1]. N-Palmitoyl-D-sphingomyelin (Sphingomyelin 16:0) (Compound SM-03) can be used for the synthesis of lipid nanoparticles[2].
References
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
[2] Dandan LING, et al. Lipid compounds and lipid nanoparticle compositions. Patent. WO2023056914.
13C C16 Sphingomyelin (d18:1/16:0) Preparation Products And Raw materials
Raw materials
Preparation Products
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