ChemicalBook > CAS DataBase List > BKI-1369
BKI-1369
- Product Name
- BKI-1369
- CAS No.
- 1951431-22-3
- Chemical Name
- BKI-1369
- Synonyms
- BKI-1369;BKI1369,BKI 1369;1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-(2-ethoxy-6-quinolinyl)-1-[(1-methyl-4-piperidinyl)methyl]-
- CBNumber
- CB74667646
- Molecular Formula
- C23H27N7O
- Formula Weight
- 417.51
- MOL File
- 1951431-22-3.mol
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BKI-1369 Property
- Boiling point:
- 626.8±50.0 °C(Predicted)
- Density
- 1.38±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: 50 mg/mL (119.76 mM)
- pka
- 9.02±0.10(Predicted)
- form
- Solid
- color
- White to off-white
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0082202
- Product name
- BKI-1369
- Purity
- 99.71%
- Packaging
- 5mg
- Price
- $500
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0082202
- Product name
- BKI-1369
- Purity
- 99.71%
- Packaging
- 10mg
- Price
- $850
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0082202
- Product name
- BKI-1369
- Purity
- 99.71%
- Packaging
- 50mg
- Price
- $2400
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0082202
- Product name
- BKI-1369
- Purity
- 99.71%
- Packaging
- 100mg
- Price
- $3600
- Updated
- 2021/12/16
DC Chemicals
- Product number
- DC22637
- Product name
- BKI1369
- Purity
- >98%
- Packaging
- 10mg
- Price
- $500
- Updated
- 2021/12/16
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BKI-1369 Chemical Properties,Usage,Production
Description
BKI-1369 is a bumped kinase inhibitor (BKI). BKI-1369 increases human Ether-a-go-go-related gene (hERG)-inhibitory activity with an IC50 of 1.52 μM. BKI-1369 reduces the parasite burden and diseases severity in the gnotobiotic pig model. BKI-1369 has been well characterized for potency, stability, metabolism, toxicity, pharmacokinetics and is potent against C. parvum in infected mice and calves[1]. IC50: 1.52 μM (hERG)[1]
References
[1]. Lee S, et al. Therapeutic Efficacy of Bumped Kinase Inhibitor 1369 in a Pig Model of Acute Diarrhea Caused by Cryptosporidium hominis. Antimicrob Agents Chemother. 2018 Jun 26;62(7).
BKI-1369 Preparation Products And Raw materials
Raw materials
Preparation Products
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BKI-1369 Suppliers
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- United States
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