NSC117079

Product Name: NSC117079
CAS No.: 500363-63-3
Chemical Name: NSC117079
Synonyms: NSC117079;NSC-117079,NSC117079;2-Anthracenesulfonic acid, 1-amino-4-[[3-(aminosulfonyl)phenyl]amino]-9,10-dihydro-9,10-dioxo-
CBNumber: CB74668294
Molecular Formula: C20H15N3O7S2
Formula Weight: 473.48
MOL File: 500363-63-3.mol

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NSC117079 Property

Density: 1.696±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: 50 mg/mL (105.60 mM)
pka: -1.19±0.20(Predicted)
form: Solid
color: Pale purple to purple

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: N900415
Product name: NSC117079
Packaging: 1mg
Price: $140
Updated: 2021/12/16

TRC

Product number: N900415
Product name: NSC117079
Packaging: 2.5mg
Price: $235
Updated: 2021/12/16

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NSC117079 Chemical Properties,Usage,Production

Uses

NSC 117079, is a novel PHLPP inhibitor.

in vivo

A single intraarticular injection of the Phlpp inhibitor NSC117079 attenuates mechanical allodynia and slows articular cartilage degradation in joints with a destabilized meniscus. Animals treated with the Phlpp inhibitor seven weeks after injury maintain normal activity levels, while those in the control group travel shorter distances and are less active three months after the joint injury. NSC117079 also increases production of cartilage extracellular matrix components (glycosaminoglycans and aggrecan) in over 90% of human articular cartilage explants from osteoarthritis patients and increased phosphorylation of Phlpp1 substrates (AKT2, ERK1/2 and PKC) in human articular chondrocytes^[1].

NSC117079 Preparation Products And Raw materials

Raw materials

Preparation Products

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NSC117079 Suppliers

China 24 United States 6 Global 30

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
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Email: info@efebio.com
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Tianjin Kailiqi Biotechnology Co., Ltd.

Tel: 15076683720
Fax: 022-23754520
Email: klq@cw-bio.com
Country: China
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Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 18101056239
Email: 3193328036@qq.com
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
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InvivoChem

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ChemeGen(Shanghai) Biotechnology Co.,Ltd.

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Email: sales@chemegen.com
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Shanghai hongqu biomedical technology co. LTD

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ShangHai ChuanQian Chemcial Technique Centre

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Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
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InvivoChem

Tel: 13549236410
Email: sales@invivochem.cn
Country: China
ProdList: 6753
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500363-63-3, NSC117079Related Search:

NSC117079

2-Anthracenesulfonic acid, 1-amino-4-[[3-(aminosulfonyl)phenyl]amino]-9,10-dihydro-9,10-dioxo-

NSC-117079,NSC117079

500363-63-3