ChemicalBook > CAS DataBase List > S55746

S55746

Product Name
S55746
CAS No.
1448584-12-0
Chemical Name
S55746
Synonyms
BLC201;S55746;S55746 (BLC201);BCL-201 (S55746);S55746(S055746,BCL201);S55746 (Synonyms: BLC201);inhibit,BCL-201,Inhibitor,Bcl-2 Family,S55746,S-55746,BCL 201,BCL201,S 55746;N-(4-hydroxyphenyl)-3-[6-[(3S)-3-(morpholin-4-ylmethyl)-3,4-dihydro-1H-isoquinoline-2-carbonyl]-1,3-benzodioxol-5-yl]-N-phenyl-5,6,7,8-tetrahydroindolizine-1-carboxamide;(S)-N-(4-Hydroxyphenyl)-3-(6-(3-(morpholinomethyl)-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)benzo[d][1,3]dioxol-5-yl)-N-phenyl-5,6,7,8-tetrahydroindolizine-1-carboxamide;1-Indolizinecarboxamide, 3-[6-[[(3S)-3,4-dihydro-3-(4-morpholinylmethyl)-2(1H)-isoquinolinyl]carbonyl]-1,3-benzodioxol-5-yl]-5,6,7,8-tetrahydro-N-(4-hydroxyphenyl)-N-phenyl-
CBNumber
CB74668476
Molecular Formula
C43H42N4O6
Formula Weight
710.82
MOL File
1448584-12-0.mol
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S55746 Property

storage temp. 
Store at -20°C
solubility 
DMSO : 50 mg/mL (70.34 mM);Water : < 0.1 mg/mL (insoluble)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

DC Chemicals
Product number
DC12163
Product name
S55746(BLC201)
Purity
>98%
Packaging
100mg
Price
$1300
Updated
2021/12/16
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S55746 Chemical Properties,Usage,Production

Description

S55746 (Bcl201, Servier-1) is orally available and has been reported to effectively kill cancer cells that overexpress Bcl-2 using both in vitro and in vivo models. Currently, S55746 as a single agent is in phase-I trials in relapsed or refractory CLL patients. As a sensitizing agent, S55746 is currently being tested for a combination use with PI3Kδinhibitor for follicular lymphoma and mantle cell lymphoma.

S55746 Preparation Products And Raw materials

Raw materials

Preparation Products

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S55746 Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58

1448584-12-0, S55746Related Search:


  • S55746
  • S55746(S055746,BCL201)
  • S55746 (Synonyms: BLC201)
  • S55746 (BLC201)
  • N-(4-hydroxyphenyl)-3-[6-[(3S)-3-(morpholin-4-ylmethyl)-3,4-dihydro-1H-isoquinoline-2-carbonyl]-1,3-benzodioxol-5-yl]-N-phenyl-5,6,7,8-tetrahydroindolizine-1-carboxamide
  • BLC201
  • 1-Indolizinecarboxamide, 3-[6-[[(3S)-3,4-dihydro-3-(4-morpholinylmethyl)-2(1H)-isoquinolinyl]carbonyl]-1,3-benzodioxol-5-yl]-5,6,7,8-tetrahydro-N-(4-hydroxyphenyl)-N-phenyl-
  • inhibit,BCL-201,Inhibitor,Bcl-2 Family,S55746,S-55746,BCL 201,BCL201,S 55746
  • BCL-201 (S55746)
  • (S)-N-(4-Hydroxyphenyl)-3-(6-(3-(morpholinomethyl)-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)benzo[d][1,3]dioxol-5-yl)-N-phenyl-5,6,7,8-tetrahydroindolizine-1-carboxamide , S55746
  • (S)-N-(4-Hydroxyphenyl)-3-(6-(3-(morpholinomethyl)-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)benzo[d][1,3]dioxol-5-yl)-N-phenyl-5,6,7,8-tetrahydroindolizine-1-carboxamide
  • 1448584-12-0
  • C43H42N4O6