TH1020

Uses

Product Name: TH1020
CAS No.: 1841460-82-9
Chemical Name: TH1020
Synonyms: TH1020;TH1020 >=95% (HPLC);4-[[4-(Phenylmethyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-pyrido[3',2';4-[[4-(Phenylmethyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-pyrido[3',2';4-((4-Benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine;4-((4-Benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine;4-[[4-(Phenylmethyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-pyrido[3',2':4,5]thieno[3,2-d]pyrimidine;Pyrido[3',2':4,5]thieno[3,2-d]pyrimidine, 4-[[4-(phenylmethyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-;interaction,inhibit,Bacterial,flagellin,TH-1020,TH1020,Toll-like Receptor (TLR),TLR5,protein-protein,TNF-α,Inhibitor,TH 1020;6-{[4-benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-8-thia-3,5,10-triazatricyclo[7.4.0.02,?]trideca-1(9),2(7),3,5,10,12-hexaene
CBNumber: CB74670635
Molecular Formula: C23H15N7S2
Formula Weight: 453.54
MOL File: 1841460-82-9.mol

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TH1020 Property

Boiling point:: 765.8±70.0 °C(Predicted)
Density: 1.51±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: Chloroform: 1 mg/ml
form: powder
pka: 1.92±0.10(Predicted)
color: white to beige

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1741
Product name: TH1020
Purity: ≥95% (HPLC)
Packaging: 5MG
Price: $107
Updated: 2023/06/20

Sigma-Aldrich

Product number: SML1741
Product name: TH1020
Purity: ≥95% (HPLC)
Packaging: 25MG
Price: $434
Updated: 2023/06/20

Tocris

Product number: 6191
Product name: TH1020
Purity: ≥98%(HPLC)
Packaging: 10
Price: $132
Updated: 2021/12/16

Tocris

Product number: 6191
Product name: TH1020
Purity: ≥98%(HPLC)
Packaging: 50
Price: $552
Updated: 2021/12/16

TRC

Product number: T430010
Product name: TH1020
Packaging: 50mg
Price: $525
Updated: 2021/12/16

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TH1020 Chemical Properties,Usage,Production

Uses

TH 1020 is a toll-like receptor 5 (TLR5)/flagellin complex inhibitor.

Uses

TH1020 has been used to inhibit toll-like receptor 5 (TLR5) in porcine intestinal epithelial monolayer cells and mice.

Biochem/physiol Actions

TH1020 is a non-cytotoxic non-cytotoxic toll-like receptor 5 (TLR5)/flagellin complex inhibitor. TH1020 selectively prevents flagellin-induced TLR5 signaling without affecting ligands-induced activation of TLR2, TLR3, TLR4, TLR7 or TLR8.

storage

Store at +4°C

TH1020 Preparation Products And Raw materials

Raw materials

Preparation Products

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TH1020 Suppliers

China 25 United Kingdom 1 United States 6 Global 32

Jingmo (Xiamen) Biotechnology Co., Ltd

Tel: 13621943973; 13621943973
Email: sales@jamxmpharmatech.com
Country: China
ProdList: 1111
Advantage: 58

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 14055
Advantage: 65

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4566
Advantage: 55

Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 7296
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 4009686088
Email: 3193328036@qq.com
Country: China
ProdList: 29785
Advantage: 68

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
Advantage: 58

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6777
Advantage: 58

Jiangsu aikang biomedical research and development co., LTD

Tel: 025-66110311 13155353615
Email: qzhang@aikonchem.com
Country: China
ProdList: 15527
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
Advantage: 58

1841460-82-9, TH1020Related Search:

TH1020

4-[[4-(Phenylmethyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-pyrido[3',2':4,5]thieno[3,2-d]pyrimidine

4-[[4-(Phenylmethyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-pyrido[3',2'

TH1020 >=95% (HPLC)

4-((4-Benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine

interaction,inhibit,Bacterial,flagellin,TH-1020,TH1020,Toll-like Receptor (TLR),TLR5,protein-protein,TNF-α,Inhibitor,TH 1020

Pyrido[3',2':4,5]thieno[3,2-d]pyrimidine, 4-[[4-(phenylmethyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-

4-((4-Benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine

6-{[4-benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-8-thia-3,5,10-triazatricyclo[7.4.0.02,?]trideca-1(9),2(7),3,5,10,12-hexaene

4-[[4-(Phenylmethyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-pyrido[3',2'

1841460-82-9