ChemicalBook > CAS DataBase List > 2'-Chloro-N6-cyclopentyl-2'-fluoro-beta-D-arabinoadenosine

2'-Chloro-N6-cyclopentyl-2'-fluoro-beta-D-arabinoadenosine

Product Name
2'-Chloro-N6-cyclopentyl-2'-fluoro-beta-D-arabinoadenosine
CAS No.
2216764-33-7
Chemical Name
2'-Chloro-N6-cyclopentyl-2'-fluoro-beta-D-arabinoadenosine
Synonyms
2-Chloro-N6-cyclopentyl-2’-fluoro-β-D-arabinoadenosine;2'-Chloro-N6-cyclopentyl-2'-fluoro-beta-D-arabinoadenosine;2-Chloro-N6-cyclopentyl-2’-deoxy-2’-fluoro-beta-D-arabinoadenosine;2-Chloro-N6-cyclopentyl-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine;9H-Purin-6-amine, 2-chloro-N-cyclopentyl-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-;(2R,3R,4S,5R)-5-[2-chloro-6-(cyclopentylamino)purin-9-yl]-4-fluoro-2-(hydroxymethyl)oxolan-3-ol;(2R,3R,4S,5R)-5-(2-chloro-6-(cyclopentylamino)-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol
CBNumber
CB74672402
Molecular Formula
C15H19ClFN5O3
Formula Weight
371.8
MOL File
2216764-33-7.mol
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2'-Chloro-N6-cyclopentyl-2'-fluoro-beta-D-arabinoadenosine Property

Boiling point:
583.7±60.0 °C(Predicted)
Density 
1.83±0.1 g/cm3(Predicted)
pka
12.57±0.70(Predicted)
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Hazard and Precautionary Statements (GHS)

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2'-Chloro-N6-cyclopentyl-2'-fluoro-beta-D-arabinoadenosine Chemical Properties,Usage,Production

Uses

2-Chloro-N6-cyclopentyl-2’-deoxy-2’-fluoro-beta-D-arabinoadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

2'-Chloro-N6-cyclopentyl-2'-fluoro-beta-D-arabinoadenosine Preparation Products And Raw materials

Raw materials

Preparation Products

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2'-Chloro-N6-cyclopentyl-2'-fluoro-beta-D-arabinoadenosine Suppliers

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2216764-33-7, 2'-Chloro-N6-cyclopentyl-2'-fluoro-beta-D-arabinoadenosineRelated Search:


  • 2'-Chloro-N6-cyclopentyl-2'-fluoro-beta-D-arabinoadenosine
  • 2-Chloro-N6-cyclopentyl-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine
  • 9H-Purin-6-amine, 2-chloro-N-cyclopentyl-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-
  • 2-Chloro-N6-cyclopentyl-2’-fluoro-β-D-arabinoadenosine
  • (2R,3R,4S,5R)-5-[2-chloro-6-(cyclopentylamino)purin-9-yl]-4-fluoro-2-(hydroxymethyl)oxolan-3-ol
  • 2-Chloro-N6-cyclopentyl-2’-deoxy-2’-fluoro-beta-D-arabinoadenosine
  • (2R,3R,4S,5R)-5-(2-chloro-6-(cyclopentylamino)-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol
  • 2216764-33-7
  • C15H19ClFN5O3