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N6-(3-Trifluoromethylbenzyl)-2'-C-methyl adenosine

Product Name
N6-(3-Trifluoromethylbenzyl)-2'-C-methyl adenosine
CAS No.
2305415-78-3
Chemical Name
N6-(3-Trifluoromethylbenzyl)-2'-C-methyl adenosine
Synonyms
N6-(3-Trifluoromethylbenzyl)-2’-C-methyladenosine;N6-(3-Trifluoromethylbenzyl)-2'-C-methyl adenosine;(2R,3R,4R,5R)-5-(hydroxymethyl)-3-methyl-2-(6-((3-(trifluoromethyl)benzyl)amino)-9H-purin-9-yl)tetrahydrofuran-3,4-diol
CBNumber
CB74672523
Molecular Formula
C19H20F3N5O4
Formula Weight
439.4
MOL File
2305415-78-3.mol
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N6-(3-Trifluoromethylbenzyl)-2'-C-methyl adenosine Property

Boiling point:
655.7±65.0 °C(Predicted)
Density 
1.62±0.1 g/cm3(Predicted)
pka
13.18±0.70(Predicted)
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Hazard and Precautionary Statements (GHS)

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N6-(3-Trifluoromethylbenzyl)-2'-C-methyl adenosine Chemical Properties,Usage,Production

Uses

N6-(3-Trifluoromethylbenzyl)-2’-C-methyl adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
[2] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020

N6-(3-Trifluoromethylbenzyl)-2'-C-methyl adenosine Preparation Products And Raw materials

Raw materials

Preparation Products

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N6-(3-Trifluoromethylbenzyl)-2'-C-methyl adenosine Suppliers

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2305415-78-3, N6-(3-Trifluoromethylbenzyl)-2'-C-methyl adenosineRelated Search:


  • N6-(3-Trifluoromethylbenzyl)-2'-C-methyl adenosine
  • N6-(3-Trifluoromethylbenzyl)-2’-C-methyladenosine
  • (2R,3R,4R,5R)-5-(hydroxymethyl)-3-methyl-2-(6-((3-(trifluoromethyl)benzyl)amino)-9H-purin-9-yl)tetrahydrofuran-3,4-diol
  • 2305415-78-3