ETHYL 3-OXO-3-PYRAZIN-2-YL-PROPIONATE
Uses- Product Name
- ETHYL 3-OXO-3-PYRAZIN-2-YL-PROPIONATE
- CAS No.
- 62124-77-0
- Chemical Name
- ETHYL 3-OXO-3-PYRAZIN-2-YL-PROPIONATE
- Synonyms
- ethyl beta-oxopyrazinepropionate;Ethyl 3-oxo-3-pyrazinylpropionate;Ethyl 3-oxo-3-pyrazin-2-yl-propiote;ETHYL 3-OXO-3-PYRAZIN-2-YL-PROPIONATE;Ethyl 3-(2-Pyrazinyl)-3-oxopropanoate;Ethyl 3-oxo-3-(pyrazin-2-yl)propanoate;2-Ethoxycarbonylmethylcarbonylpyrazine;β-Oxo-2-pyrazinepropionic acid ethyl ester;beta-Oxo-2-pyrazinepropanoic acid ethyl ester;2-Pyrazinepropanoic acid, β-oxo-, ethyl ester
- CBNumber
- CB7471230
- Molecular Formula
- C9H10N2O3
- Formula Weight
- 194.19
- MOL File
- 62124-77-0.mol
ETHYL 3-OXO-3-PYRAZIN-2-YL-PROPIONATE Property
- Melting point:
- 61.0 to 65.0 °C
- Boiling point:
- 120°C/2mmHg(lit.)
- storage temp.
- Store at room temperature
- form
- powder to crystal
- color
- Light yellow to Yellow to Orange
- InChI
- 1S/C9H10N2O3/c1-2-14-9(13)5-8(12)7-6-10-3-4-11-7/h3-4,6H,2,5H2,1H3
- InChIKey
- OPBDMDPBJKVMNL-UHFFFAOYSA-N
- SMILES
- O=C(C1=NC=CN=C1)CC(OCC)=O
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- JRD0707
- Product name
- Ethyl 3-oxo-3-(pyrazin-2-yl)propanoate
- Packaging
- 1g
- Price
- $179
- Updated
- 2025/07/31
- Product number
- E1271
- Product name
- Ethyl 3-Oxo-3-(pyrazin-2-yl)propionate
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $106
- Updated
- 2025/07/31
- Product number
- E925408
- Product name
- Ethyl 3-Oxo-3-(pyrazin-2-yl)propionate
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- OR965038
- Product name
- Ethyl 3-Oxo-3-(pyrazin-2-yl)propionate
- Purity
- 98%
- Packaging
- 1g
- Price
- $115
- Updated
- 2021/12/16
- Product number
- 6700AH
- Product name
- Ethyl 3-Oxo-3-(pyrazin-2-yl)propionate
- Packaging
- 1g
- Price
- $131
- Updated
- 2021/12/16
ETHYL 3-OXO-3-PYRAZIN-2-YL-PROPIONATE Chemical Properties,Usage,Production
Uses
Ethyl 3-(2-pyrazinyl)-3-oxopropionate is an organic intermediate that can be obtained by reacting methyl pyrazine-2-carboxylate and ethyl formate or by reacting diethyl malonate and pyrazine-2-carbonyl chloride.
Synthesis
In a three-necked flask equipped with a mechanical stirrer, condenser, and dropping funnel, methyl pyrazine-2-carboxylate (10 g, 72.4 mmol, 1 eq.) was dissolved dropwise over 35-40 min. into a stirred 90 mL solution of sodium methanolate (25% MeOH, 27.54 mL, 72.4 mmol, 1 eq.) in toluene in a 115 mL of ethyl formate solution. A yellow precipitate was formed. Stirring was continued at 110??C for 3 hours. The reaction was cooled and the yellow precipitate was filtered and washed with a small amount of toluene. The solid was dissolved in 200 mL of saturated ammonium chloride and 400 mL of EtOAc. The aqueous layer was extracted twice with EtOAc. The combined organic layers were dried over magnesium sulfate, filtered and evaporated to give ethyl 3-(2-pyrazinyl)-3-oxopropanoate. Yellow solid, yield 6.52 g, 50%.
ETHYL 3-OXO-3-PYRAZIN-2-YL-PROPIONATE Preparation Products And Raw materials
Raw materials
Preparation Products
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