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alloc-L-Val-L-Ala-PABOH

Product Name
alloc-L-Val-L-Ala-PABOH
CAS No.
1343407-91-9
Chemical Name
alloc-L-Val-L-Ala-PABOH
Synonyms
Alloc-Val-Ala-pAB;Alloc-L-Val-Ala-PAB-OH;alloc-L-Val-L-Ala-PABOH;N-(Allyloxycarbonyl)-L-valyl-[4-(hydroxymethyl)phenyl]-L-alaninamide;L-Alaninamide, N-[(2-propen-1-yloxy)carbonyl]-L-valyl-N-[4-(hydroxymethyl)phenyl]-;Allyl [(S)-1-[[(S)-1-[[4-(Hydroxymethyl)phenyl]amino]-1-oxo-2-propyl]amino]-3-methyl-1-oxo-2-butyl]carbamate;prop-2-en-1-yl N-[(1S)-1-{[(1S)-1-[(4-(hydroxymethyl)phenyl)carbamoyl]ethyl]carbamoyl}-2-methylpropyl]carbamate;allyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate;prop-2-enyl N-[(2S)-1-[[(2S)-1-[4-(hydroxymethyl)anilino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamate
CBNumber
CB74718506
Molecular Formula
C19H27N3O5
Formula Weight
377.43
MOL File
1343407-91-9.mol
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alloc-L-Val-L-Ala-PABOH Property

Melting point:
227 °C
Boiling point:
660.3±55.0 °C(Predicted)
Density 
1.194±0.06 g/cm3(Predicted)
pka
11.52±0.46(Predicted)
form 
powder to crystal
color 
White to Almost white
InChIKey
YWKFGPPNBVPIDP-BBRMVZONSA-N
SMILES
C(N)(=O)[C@H](C)N(C(=O)[C@H](C(C)C)NC(OCC=C)=O)C1=CC=C(CO)C=C1
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Safety

HS Code 
2924.29.7790
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TCI Chemical
Product number
A3347
Product name
Alloc-Val-Ala-PAB-OH
Packaging
250MG
Price
$545
Updated
2024/03/01
AK Scientific
Product number
6462DT
Product name
Prop-2-enylN-[(2S)-1-[[(2S)-1-[4-(hydroxymethyl)anilino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamate
Packaging
250mg
Price
$684
Updated
2021/12/16
ChemScene
Product number
CS-0093977
Product name
Allyl((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate
Packaging
1g
Price
$1365
Updated
2021/12/16
Acrotein
Product number
AS01376
Product name
Alloc-Val-Ala-pAB
Purity
97%
Packaging
0.25g
Price
$293.3
Updated
2021/12/16
Acrotein
Product number
AS01376
Product name
Alloc-Val-Ala-pAB
Purity
97%
Packaging
0.5g
Price
$440
Updated
2021/12/16
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alloc-L-Val-L-Ala-PABOH Chemical Properties,Usage,Production

Description

Alloc-Val-Ala-PAB-OH is a peptide linker with a terminal Alloc protecting group. The peptide chain can act as a cleavable linker in drug design, such as in antibody drug conjugates (ADC). The Alloc group is stable to treatment with piperidine and TFA, and can be removed in neutral conditions with catalytic amounts of Pd(PPh3)4 in the presence of PhSiH3. This allows the allyl system to work orthogonality with the most common protecting groups.

alloc-L-Val-L-Ala-PABOH Preparation Products And Raw materials

Raw materials

Preparation Products

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alloc-L-Val-L-Ala-PABOH Suppliers

SINO High Goal Chemical Technology Co., Ltd.
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View Lastest Price from alloc-L-Val-L-Ala-PABOH manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Alloc-Val-Ala-PAB 1343407-91-9
Price
US $0.00/g
Min. Order
1g
Purity
>95.00%
Supply Ability
1g
Release date
2024-03-29

1343407-91-9, alloc-L-Val-L-Ala-PABOHRelated Search:


  • alloc-L-Val-L-Ala-PABOH
  • Alloc-Val-Ala-pAB
  • prop-2-enyl N-[(2S)-1-[[(2S)-1-[4-(hydroxymethyl)anilino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamate
  • L-Alaninamide, N-[(2-propen-1-yloxy)carbonyl]-L-valyl-N-[4-(hydroxymethyl)phenyl]-
  • N-(Allyloxycarbonyl)-L-valyl-[4-(hydroxymethyl)phenyl]-L-alaninamide
  • allyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate
  • Alloc-L-Val-Ala-PAB-OH
  • Allyl [(S)-1-[[(S)-1-[[4-(Hydroxymethyl)phenyl]amino]-1-oxo-2-propyl]amino]-3-methyl-1-oxo-2-butyl]carbamate
  • prop-2-en-1-yl N-[(1S)-1-{[(1S)-1-[(4-(hydroxymethyl)phenyl)carbamoyl]ethyl]carbamoyl}-2-methylpropyl]carbamate
  • 1343407-91-9
  • ADCs Linkers