ChemicalBook > CAS DataBase List > MCAAD-3
MCAAD-3
- Product Name
- MCAAD-3
- CAS No.
- 1625629-51-7
- Chemical Name
- MCAAD-3
- Synonyms
- MCAAD-3;MCAAD-3, Near-infrared probe for imaging of amyloid plaques;Methyl (2E,4E,6E)-2-cyano-7-(4-(dimethylamino)phenyl)hepta-2,4,6-trienoate;2,4,6-Heptatrienoic acid, 2-cyano-7-[4-(dimethylamino)phenyl]-, methyl ester, (2E,4E,6E)-
- CBNumber
- CB74718632
- Molecular Formula
- C17H18N2O2
- Formula Weight
- 282.34
- MOL File
- 1625629-51-7.mol
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MCAAD-3 Property
- Boiling point:
- 484.6±45.0 °C(Predicted)
- Density
- 1.123±0.06 g/cm3(Predicted)
- pka
- 4.73±0.24(Predicted)
- form
- Solid
- color
- Brown to black
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MCAAD-3 Chemical Properties,Usage,Production
Uses
MCAAD-3 is a near-infrared Aβ imaging probe with blood-brain barrier penetrability. MCAAD-3 has a strong affinity for Aβ polymers (Ki >106 nM) and can label Aβ plaques in the brains of transgenic mice[1].
References
[1] Fu H, et al. Evaluation of molecules based on the electron donor-acceptor architecture as near-infrared β-amyloidal-targeting probes. Chem Commun (Camb). 2014 Oct 14;50(80):11875-8. DOI:10.1039/c4cc04907a
MCAAD-3 Preparation Products And Raw materials
Raw materials
Preparation Products
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MCAAD-3 Suppliers
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