8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE

ChemicalBook > CAS DataBase List > 8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE

8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE

Product Name: 8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE
CAS No.: 102146-07-6
Chemical Name: 8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE
Synonyms: DPCPX;1,3-Dpcpx;PD 116,948;8-CYCLOPENTYL-1;PD-116948(DPCPX);DPCPX, PD 116,948;3-DIPROPYLXANTHINE;DPCPX, A1 antagonist;Levodropropizine Impurity 15;cyclopentyl-1,3-dipropylxanthine
CBNumber: CB7472080
Molecular Formula: C16H24N4O2
Formula Weight: 304.39
MOL File: 102146-07-6.mol

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8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE Property

Melting point:: 178°C
Boiling point:: 535.1±42.0 °C(Predicted)
Density: 1.195±0.06 g/cm3(Predicted)
storage temp.: Store at RT
solubility: DMSO: >10 mg/mL
form: solid
pka: 9.01±0.70(Predicted)
color: white
Stability:: Store tightly sealed at RT; Solutions at 4 deg C for several days
CAS DataBase Reference: 102146-07-6(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C101
Product name: 8-Cyclopentyl-1,3-dipropylxanthine
Purity: solid
Packaging: 25mg
Price: $91.6
Updated: 2024/03/01

Sigma-Aldrich

Product number: C101
Product name: 8-Cyclopentyl-1,3-dipropylxanthine
Purity: solid
Packaging: 100mg
Price: $200
Updated: 2024/03/01

Tocris

Product number: 0439
Product name: DPCPX
Purity: ≥99%(HPLC)
Packaging: 100
Price: $195
Updated: 2021/12/16

TRC

Product number: C988500
Product name: 8-Cyclopentyl-1,3-dipropylxanthine
Packaging: 50mg
Price: $80
Updated: 2021/12/16

Usbiological

Product number: 255190
Product name: DPCPX
Packaging: 100mg
Price: $446
Updated: 2021/12/16

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8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

DPCPX is a potent and very selective A1-adenosine receptor antagonist, with a Ki of 0.46 nM for A1 receptors in rat whole-brain membranes. Its 740-fold A1-selectivity is the highest reported for an adenosine antagonist

Uses

8-Cyclopentyl-1,3-dipropylxanthine has been used as an adenosine receptor (A1AR) antagonist in macrophages and human umbilical vein endothelial cells (HUVECs). It has also been used as A1AR antagonist in MCF-7 breast cancer cell line to test its anti-cancer effect.

Definition

ChEBI: An oxopurine that is 7H-xanthine substituted at positions 1 and 3 by propyl groups and at position 8 by a cyclohexyl group.

Biological Activity

Potent and selective A 1 adenosine receptor antagonist, both in vitro and in vivo . K i values are 3.9, 130, 50 and 4000 nM for human A 1 , A 2A , A 2B and A 3 receptors respectively.

Biochem/physiol Actions

8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) is a selective A1?adenosine receptor antagonist. DPCPX possesses anti-cancer functionality. It induces apoptosis in breast cancer cells and favors mRNA expression of caspases.

storage

Room temperature

8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE Preparation Products And Raw materials

Raw materials

Preparation Products

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8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE Suppliers

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102146-07-6, 8-CYCLOPENTYL-1,3-DIPROPYLXANTHINERelated Search:

N-PROPYLBENZENE Cyclohexylbenzene Trichloropropylsilane 8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE [DPCPX] KFM 19 8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE CYCLOPENTYL-1,3-DIPROPYLXANTHINE, 8-[DIPROPYL-2,3-3H(N)]- MIDAXIFYLLINE [PROPYL-3H]8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE 8-CYCLOPENTYL-N3-[3-(4-(FLUOROSULFONYL)BENZOYLOXY)PROPYL]-N1-PROPYLXANTHINE 8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE [DIPROPYL-2,3-3H] 1-BUTYL-8-(HEXAHYDRO-2,5-METHANOPENTALEN-3A(1H)-YL)-3,7-DIHYDRO-3-(3-HYDROXYPROPYL)-1H-PURINE-2,6-DIONE

DPCPX, PD 116,948

8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE(DPCPX,1,3-DIPROPYL-8-CYCLOPENTYLXANTHINE)

cyclopentyl-1,3-dipropylxanthine

1,3-Dipropyl-8-cyclopentylxanthine, DPCPX, PD 116,948

1,3-Dipropyl-8-cyclopentyl-7H-purine-2,6(1H,3H)-dione

8-Cyclopentyl-3,7-dihydro-1,3-dipropyl-1H-purine-2,6-dione

1,3-Dpcpx

1H-Purine-2,6-dione, 8-cyclopentyl-3,7-dihydro-1,3-dipropyl-

8-Cyclopentyl-3,7-dihydro-1,3-dipropyl-1H-purin-2,6-dione

PD-116948(DPCPX)

8-cyclopentyl-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione

8-Cyclopentyl-1,3-dipropyl-1H-purine-2,6(3H,7H)-dione

8-Cyclopentyl-3,9-dihydro-1,3-dipropyl-1H-purine-2,6-dione

PD 116,948

1,3-DIPROPYL-8-CYCLOPENTYLXANTHINE

8-CYCLOPENTYL-1

8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE

DPCPX

8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE SELEC TIVE A1 ADENOSIN

3-DIPROPYLXANTHINE

1H-Purine-2,6-dione, 8-cyclopentyl-3,9-dihydro-1,3-dipropyl-

P1 receptor,inhibit,Inhibitor,PD-116948,Adenosine Receptor,DPCPX,PD116948

8-Cyclopentyl-3,9-dihydro-1,3-dipropyl-1H-purin-2,6-dione

8-Cyclopentyl-1,3-dipropylxanthine solid

Levodropropizine Impurity 15

DPCPX, A1 antagonist

102146-07-6

C16H24N4O2

Adenosine receptor

All Inhibitors

Inhibitors

Heterocycles

Neurochemicals