1-[3-(3,4-METHYLENEDIOXYPHENOXY)PROPYL]-4-PHENYL-PIPERAZINE MALEATE Property

Boiling point:

496.9±45.0 °C(Predicted)

Density 

1.188±0.06 g/cm3(Predicted)

storage temp. 

Store at RT

solubility 

<45.65mg/ml in DMSO

form 

solid

pka

7.42±0.10(Predicted)

color 

Off-white

Hazard and Precautionary Statements (GHS)

1-[3-(3,4-METHYLENEDIOXYPHENOXY)PROPYL]-4-PHENYL-PIPERAZINE MALEATE Chemical Properties,Usage,Production

Uses

BP 554 Maleate was used to study the methods for the classification and diagnosis of scoliosis.

Definition

ChEBI: 1-[3-(1,3-benzodioxol-5-yloxy)propyl]-4-phenylpiperazine is a member of piperazines.

Biological Activity

Selective 5-HT 1A agonist.

References

[1]. matsuda t, seong yh, aono h, et al. agonist activity of a novel compound, 1-[3-(3,4-methylenedioxyphenoxy)propyl]-4-phenyl piperazine (bp-554), at central 5-ht1a receptors. eur j pharmacol, 1989, 170(1-2): 75-82.
[2]. galter d, unsicker k. sequential activation of the 5-ht1(a) serotonin receptor and trkb induces the serotonergic neuronal phenotype. mol cell neurosci, 2000, 15(5): 446-455.
[3]. rauch a, rainer g, logothetis nk. the effect of a serotonin-induced dissociation between spiking and perisynaptic activity on bold functional mri. proc natl acad sci u s a, 2008, 105(18): 6759-6764.