ChemicalBook > CAS DataBase List > MCH-1 antagonist 1
MCH-1 antagonist 1
- Product Name
- MCH-1 antagonist 1
- CAS No.
- 1039825-68-7
- Chemical Name
- MCH-1 antagonist 1
- Synonyms
- MCH-1 antagonist 1;MCH1 antagonist 1,MCH 1 antagonist 1;2(1H)-Pyridinone, 4-(phenylmethoxy)-1-[1-[2-(1-pyrrolidinyl)ethyl]-1H-indazol-5-yl]-
- CBNumber
- CB74796667
- Molecular Formula
- C25H26N4O2
- Formula Weight
- 414.5
- MOL File
- 1039825-68-7.mol
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MCH-1 antagonist 1 Property
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
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MCH-1 antagonist 1 Chemical Properties,Usage,Production
Uses
MCH-1 Antagonist 1, is a potent melanin concentrating hormone (MCH-1) antagonist.
in vivo
MCH-1 antagonist 1 is administered to male C57BL/6J DIO mice to assess their pharmacokinetic profile. Effect of MCH-1 antagonist 1 (dosed at 30 mg/kg, po) is measured on the body weight of DIO mice with the AUC0-6 h of 14760 h*ng/mL[1].
IC 50
MCH-1: 2.6 nM (Ki); CYP3A4: 10 μM (IC50)
MCH-1 antagonist 1 Preparation Products And Raw materials
Raw materials
Preparation Products
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