ChemicalBook > CAS DataBase List > CGS 15435

CGS 15435

Product Name
CGS 15435
CAS No.
95853-92-2
Chemical Name
CGS 15435
Synonyms
CGS 15435;CGS 15435, 10 mM in DMSO;1H-Indole-3-hexanoic acid, 5-chloro-1-methyl-2-(3-pyridinyl)-
CBNumber
CB74797033
Molecular Formula
C20H21ClN2O2
Formula Weight
356.85
MOL File
95853-92-2.mol
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CGS 15435 Property

storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

CSNpharm
Product number
CSN21322
Product name
CGS15435
Packaging
5mg
Price
$1442
Updated
2021/12/16
CSNpharm
Product number
CSN21322
Product name
CGS15435
Packaging
10mg
Price
$2308
Updated
2021/12/16
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CGS 15435 Chemical Properties,Usage,Production

Uses

CGS 15435, is a thromboxane (TxA2) synthetase inhibitor. It has also high selectivity for Tx synthetase 100000-fold greater than that for cyclooxygenase, PGI2 synthetase and lipoxygenase enzymes.

in vivo

CGS 15435 has a long duration of action, since the increases in the plasma levels of TxB2 are prevented even at 24 h after CGS 15435 administration. CGS 15435 significantly inhibits TxB2 formation 4, 6, 12 and 24 h after dosing. Administration of CGS 15435 0.25 or 24 h prior to Arachidonic acid (AA) produced no increase in TxB2 in the surviving animals (4/4 and 5/6, respectively). The final TxB2 levels in the CGS15435A (0.25 and 24 h pretreatment) groups are significantly lower (P<0.05) than those seen in the AA or the Dazoxiben (2 h pretreatment) groups[1].

IC 50

TXA2: 1 nM (IC50)

CGS 15435 Preparation Products And Raw materials

Raw materials

Preparation Products

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CGS 15435 Suppliers

China 13 United States 3 Global 16
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9729
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24961
Advantage
58
Suzhou Haiben Pharmaceutical Co., Ltd
Tel
19353112242
Email
1816280386@qq.com
Country
China
ProdList
8045
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
11973
Advantage
58
Sangon Biotech (Shanghai) Co.,Ltd.
Tel
400-821-026
Email
Sales@sangon.com
Country
China
ProdList
6710
Advantage
58
Biosynth Biological Technology (Suzhou) Co Ltd
Tel
51288865780
Email
sales@biosynth.com
Country
China
ProdList
6051
Advantage
58
Adooq Bioscience LLC
Tel
400-025-6535
Email
sales@adooq.cn
Country
China
ProdList
6215
Advantage
58
Taizhou Zhongzhi Biotechnology Co., Ltd
Tel
13012344321
Email
3995296515@qq.com
Country
China
ProdList
8448
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354;
Email
support@targetmol.com
Country
United States
ProdList
39035
Advantage
58

95853-92-2, CGS 15435Related Search:


  • CGS 15435
  • 1H-Indole-3-hexanoic acid, 5-chloro-1-methyl-2-(3-pyridinyl)-
  • CGS 15435, 10 mM in DMSO
  • 95853-92-2