ChemicalBook > CAS DataBase List > Firuglipel
Firuglipel
- Product Name
- Firuglipel
- CAS No.
- 1371591-51-3
- Chemical Name
- Firuglipel
- Synonyms
- Firuglipel;4-(5-((R)-1-(4-(Cyclopropanecarbonyl)phenoxy)propyl)-1,2,4-oxadiazol-3-yl)-2-fluoro-N-((R)-1-hydroxypropan-2-yl)benzamide;Benzamide, 4-[5-[(1R)-1-[4-(cyclopropylcarbonyl)phenoxy]propyl]-1,2,4-oxadiazol-3-yl]-2-fluoro-N-[(1R)-2-hydroxy-1-methylethyl]-
- CBNumber
- CB74806669
- Molecular Formula
- C25H26FN3O5
- Formula Weight
- 467.49
- MOL File
- 1371591-51-3.mol
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Firuglipel Property
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Solid
- color
- White to off-white
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Firuglipel Chemical Properties,Usage,Production
Uses
Firuglipel (DS-8500a) is an orally available, potent and selective GPR119 agonist.
in vivo
Firuglipel (DS-8500a) (1-30 mg/kg) upregulates glucagon-like peptide-1 and enhances glucose-dependent insulin secretion and improves glucose homeostasis in type 2 diabetic rats[1].
References
[1] Matsumoto K, et al. DS-8500a, an Orally Available G Protein-Coupled Receptor 119 Agonist, Upregulates Glucagon-Like Peptide-1 and Enhances Glucose-Dependent Insulin Secretion and Improves Glucose Homeostasis in Type 2 Diabetic Rats. J Pharmacol Exp Ther. 2018 Dec;367(3):509-517. DOI:10.1124/jpet.118.250019
Firuglipel Preparation Products And Raw materials
Raw materials
Preparation Products
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Firuglipel Suppliers
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58
- Tel
- +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 19961
- Advantage
- 58
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View Lastest Price from Firuglipel manufacturers
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
- Product
- Firuglipel 1371591-51-3
- Price
- US $2.00-5.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-06-18