2'-Amino-2'-deoxy-5-fluoro-arabinouridine

Product Name: 2'-Amino-2'-deoxy-5-fluoro-arabinouridine
CAS No.: 2305415-81-8
Chemical Name: 2'-Amino-2'-deoxy-5-fluoro-arabinouridine
Synonyms: 2’-Amino-2’-deoxy-5-fluoro-arabinouridine;2'-Amino-2'-deoxy-5-fluoro-arabinouridine;1-((2R,3S,4S,5R)-3-amino-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-fluoropyrimidine-2,4(1H,3H)-dione
CBNumber: CB74842067
Molecular Formula: C9H12FN3O5
Formula Weight: 261.21
MOL File: 2305415-81-8.mol

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2'-Amino-2'-deoxy-5-fluoro-arabinouridine Property

Density: 1.69±0.1 g/cm3(Predicted)
pka: 13.68±0.70(Predicted)

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Hazard and Precautionary Statements (GHS)

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2'-Amino-2'-deoxy-5-fluoro-arabinouridine Chemical Properties,Usage,Production

Uses

2’-Amino-2’-deoxy-5-fluoro-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20(5):218-25. DOI:10.1016/s0165-6147(99)01298-5
[2] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

2'-Amino-2'-deoxy-5-fluoro-arabinouridine Preparation Products And Raw materials

Raw materials

Preparation Products

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2'-Amino-2'-deoxy-5-fluoro-arabinouridine Suppliers

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2305415-81-8, 2'-Amino-2'-deoxy-5-fluoro-arabinouridineRelated Search:

1-beta-D-arabinofuranosyl-5-fluoro-(1H,3H)-pyrimidine-2,4-dione 5-FLUOROURIDINE-13C,15N2 5-FLUORO-2'-O-METHYLURIDINE 5'-DEOXYFLUOROURIDINE-13C,15N2 Floxuridine-13C,15N2

2'-Amino-2'-deoxy-5-fluoro-arabinouridine

2’-Amino-2’-deoxy-5-fluoro-arabinouridine

1-((2R,3S,4S,5R)-3-amino-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-fluoropyrimidine-2,4(1H,3H)-dione

2305415-81-8