Diprotin A TFA (Synonyms: Ile-Pro-Pro (TFA))

Product Name: Diprotin A TFA (Synonyms: Ile-Pro-Pro (TFA))
CAS No.: 209248-71-5
Chemical Name: Diprotin A TFA (Synonyms: Ile-Pro-Pro (TFA))
Synonyms: Diprotin A TFA;Ile-Pro-Pro (TFA);Diprotin A TFA (Ile-Pro-Pro (TFA));Diprotin A TFA (Synonyms: Ile-Pro-Pro (TFA))
CBNumber: CB74844713
Molecular Formula: C19H32F3N3O6
Formula Weight: 455.48
MOL File: 209248-71-5.mol

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Diprotin A TFA (Synonyms: Ile-Pro-Pro (TFA)) Property

storage temp.: Store at -20°C
form: Solid
color: White to off-white
Water Solubility: Water : ≥ 77.5 mg/mL (170.15 mM)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0077835
Product name: DiprotinA(TFA)
Purity: 98.80%
Packaging: 5mg
Price: $50
Updated: 2021/12/16

ChemScene

Product number: CS-0077835
Product name: DiprotinA(TFA)
Purity: 98.80%
Packaging: 10mg
Price: $70
Updated: 2021/12/16

ChemScene

Product number: CS-0077835
Product name: DiprotinA(TFA)
Purity: 98.80%
Packaging: 25mg
Price: $120
Updated: 2021/12/16

ChemScene

Product number: CS-0077835
Product name: DiprotinA(TFA)
Purity: 98.80%
Packaging: 50mg
Price: $190
Updated: 2021/12/16

DC Chemicals

Product number: DC12269
Product name: DiprotinATFA(Ile-Pro-Pro(TFA))
Purity: >98%
Packaging: 100mg
Price: $290
Updated: 2021/12/16

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Diprotin A TFA (Synonyms: Ile-Pro-Pro (TFA)) Chemical Properties,Usage,Production

Uses

Diprotin A TFA (Ile-Pro-Ile TFA) is an inhibitor of dipeptidyl peptidase IV (DPP-IV)[1].

in vivo

In the model of retinopathy of prematurity, Diprotin A increases not only retinal vascularity but also leakage. Additionally, in the murine diabetic retinopathy model, Diprotin A increases the phosphorylation of Src and VE-cadherin and aggravates vascular leakage in the retinas. Collectively, Diprotin A induces vascular leakage by augmenting the SDF-1α/CXCR4/Src/VE-cadherin signaling pathway^[1].

IC 50

DPP-4

References

[1] Lee CS, et al. Dipeptidyl Peptidase-4 Inhibitor Increases Vascular Leakage in Retina through VE-cadherin Phosphorylation. Sci Rep. 2016 Jul 6;6:29393. DOI:10.1038/srep29393

Diprotin A TFA (Synonyms: Ile-Pro-Pro (TFA)) Preparation Products And Raw materials

Raw materials

Preparation Products

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Diprotin A TFA (Synonyms: Ile-Pro-Pro (TFA)) Suppliers

China 24 United States 4 Global 28

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