Azido-PEG3-triethoxysilane

Product Name: Azido-PEG3-triethoxysilane
CAS No.: 2243566-43-8
Chemical Name: Azido-PEG3-triethoxysilane
Synonyms: N3-PEG3-triethoxysilane;Azido-PEG3-triethoxysilane;Azido-PEG3-amide-C3-triethoxysilane;N3-PEG3-CH2CH2CONH-CH2CH2CH2Si(OEt)3
CBNumber: CB74849541
Molecular Formula: C18H38N4O7Si
Formula Weight: 450.61
MOL File: 2243566-43-8.mol

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Azido-PEG3-triethoxysilane Property

solubility: Soluble in DMSO, DCM, DMF

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-24073
Product name: Azido-PEG3-triethoxysilane
Purity: 98%
Packaging: 100mg
Price: $280
Updated: 2021/12/16

BroadPharm

Product number: BP-24073
Product name: Azido-PEG3-triethoxysilane
Purity: 98%
Packaging: 250mg
Price: $450
Updated: 2021/12/16

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Azido-PEG3-triethoxysilane Chemical Properties,Usage,Production

Description

Azido-PEG3-triethoxysilane is a PEG linker containing azido and triethoxysilane moieties. The azide can be used for copper-catalyzed Click Chemistry reactions with alkynes, DBCO and BCN. The triethoxysilane moiety is used for surface modification. The hydrophilic PEG linkers increase the water solubility properties of compounds in aqueous media.

Uses

Azido-PEG3-amide-C3-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG3-amide-C3-triethoxysilane is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Azido-PEG3-triethoxysilane Preparation Products And Raw materials

Raw materials

Preparation Products

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Azido-PEG3-triethoxysilane Suppliers

China 12 United States 3 Global 15

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

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Zhengzhou Huiju Chemical Co., Ltd.

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TargetMol Chemicals Inc.

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Shaanxi Xinyan Bomei Biotechnology Co., Ltd.

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Zhengzhou Akem Chemical Co., Ltd

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Beijing Jin Ming Biotechnology Co., Ltd.

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Shanghai Easy CDMO Co.,Ltd

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TargetMol Chemicals Inc.

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Amatek Scientific Co. Ltd.

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2243566-43-8, Azido-PEG3-triethoxysilaneRelated Search:

Azido-PEG3-triethoxysilane

Azido-PEG3-amide-C3-triethoxysilane

N3-PEG3-triethoxysilane

N3-PEG3-CH2CH2CONH-CH2CH2CH2Si(OEt)3

2243566-43-8