DBCO-PEG9-amine

Product Name: DBCO-PEG9-amine
CAS No.: 2353409-99-9
Chemical Name: DBCO-PEG9-amine
Synonyms: DBCO-PEG9-amine;DBCO-PEG9-amine TFA salt;Dibenz[b,f]azocine-5(6H)-butanamide, N-(29-amino-3,6,9,12,15,18,21,24,27-nonaoxanonacos-1-yl)-11,12-didehydro-γ-oxo-
CBNumber: CB74849581
Molecular Formula: C39H57N3O11
Formula Weight: 743.9
MOL File: 2353409-99-9.mol

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DBCO-PEG9-amine Property

Boiling point:: 883.2±65.0 °C(Predicted)
Density: 1.20±0.1 g/cm3(Predicted)
solubility: Soluble in Water, DMSO, DCM, DMF
form: Oil
pka: 15.14±0.46(Predicted)
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-24150
Product name: DBCO-PEG9-amineTFAsalt
Purity: 98%
Packaging: 50mg
Price: $360
Updated: 2021/12/16

BroadPharm

Product number: BP-24150
Product name: DBCO-PEG9-amineTFAsalt
Purity: 98%
Packaging: 250mg
Price: $950
Updated: 2021/12/16

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DBCO-PEG9-amine Chemical Properties,Usage,Production

Description

DBCO-PEG9-amine is a PEG linker which contains DBCO and amine moieties. The DBCO group is commonly used in copper-free Click Chemistry reactions. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydrophilic PEG spacer increases the water solubility of the compound.

Uses

DBCO-PEG9-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG9-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

DBCO-PEG9-amine Preparation Products And Raw materials

Raw materials

Preparation Products

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DBCO-PEG9-amine Suppliers

China 20 United States 4 Global 24

Shanghai Send Pharmaceutical Technology Co., Ltd.

Tel: 021-58088081 Q2635253576
Fax: QQ3382968513
Email: hailey@shsendpharm.com
Country: China
ProdList: 1984
Advantage: 55

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
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Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
Email: 1924344760@qq.com
Country: China
ProdList: 4952
Advantage: 58

Alfa Chemistry

Tel: +1-5166625404;
Fax: 1-516-927-0118
Email: Info@alfa-chemistry.com
Country: United States
ProdList: 20405
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
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Shaanxi Xinyan Bomei Biotechnology Co., Ltd.

Tel: 13892832556
Email: 2440688701@qq.com
Country: China
ProdList: 1994
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Zhengzhou Convergence Chemical Co. LTD

Tel: 0371-0371-53736046 13393710386
Fax: QQ:2853979814
Email: 2853979814@qq.com
Country: China
ProdList: 9948
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Zhengzhou Akem Chemical Co., Ltd

Tel: 13303867194
Email: 3001317055@qq.com
Country: China
ProdList: 9679
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Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

Tel: 0431-80514535 19917294565
Email: et@chemextension.com
Country: China
ProdList: 5061
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TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

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View Lastest Price from DBCO-PEG9-amine manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: DBCO-PEG9-amine 2353409-99-9
Price: US $0.00/mg
Min. Order: 50mg
Purity: >97.00%
Supply Ability: 250
Release date: 2024-03-20

2353409-99-9, DBCO-PEG9-amineRelated Search:

DBCO-PEG9-amine

DBCO-PEG9-amine TFA salt

Dibenz[b,f]azocine-5(6H)-butanamide, N-(29-amino-3,6,9,12,15,18,21,24,27-nonaoxanonacos-1-yl)-11,12-didehydro-γ-oxo-

2353409-99-9