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DBCO-PEG9-amine

Product Name
DBCO-PEG9-amine
CAS No.
2353409-99-9
Chemical Name
DBCO-PEG9-amine
Synonyms
DBCO-PEG9-NH2;DBCO-PEG9-amine;DBCO-PEG9-amine TFA salt;Dibenz[b,f]azocine-5(6H)-butanamide, N-(29-amino-3,6,9,12,15,18,21,24,27-nonaoxanonacos-1-yl)-11,12-didehydro-γ-oxo-
CBNumber
CB74849581
Molecular Formula
C39H57N3O11
Formula Weight
743.9
MOL File
2353409-99-9.mol
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DBCO-PEG9-amine Property

Boiling point:
883.2±65.0 °C(Predicted)
Density 
1.20±0.1 g/cm3(Predicted)
solubility 
Soluble in Water, DMSO, DCM, DMF
form 
Oil
pka
15.14±0.46(Predicted)
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-24150
Product name
DBCO-PEG9-amineTFAsalt
Purity
98%
Packaging
50mg
Price
$360
Updated
2021/12/16
BroadPharm
Product number
BP-24150
Product name
DBCO-PEG9-amineTFAsalt
Purity
98%
Packaging
250mg
Price
$950
Updated
2021/12/16
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DBCO-PEG9-amine Chemical Properties,Usage,Production

Description

DBCO-PEG9-amine is a PEG linker which contains DBCO and amine moieties. The DBCO group is commonly used in copper-free Click Chemistry reactions. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydrophilic PEG spacer increases the water solubility of the compound.

Uses

DBCO-PEG9-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG9-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

DBCO-PEG9-amine Preparation Products And Raw materials

Raw materials

Preparation Products

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DBCO-PEG9-amine Suppliers

Shanghai Send Pharmaceutical Technology Co., Ltd.
Tel
50266790 18317173152
Fax
QQ3382968513
Email
Hailey@shsendpharm.com
Country
China
ProdList
904
Advantage
55
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4952
Advantage
58
Alfa Chemistry
Tel
+1-5166625404;
Fax
1-516-927-0118
Email
Info@alfa-chemistry.com
Country
United States
ProdList
20405
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32467
Advantage
58
Shaanxi Xinyan Bomei Biotechnology Co., Ltd.
Tel
13892832556
Email
2440688701@qq.com
Country
China
ProdList
1995
Advantage
58
Xiamen Sinopeg Biotech Co., Ltd.
Tel
400-9189898 17359873007
Email
sales@sinopeg.com
Country
China
ProdList
1000
Advantage
58
Zhengzhou Convergence Chemical Co. LTD
Tel
0371-0371-53736046 13393710386
Fax
QQ:2853979814
Email
3941078109@qq.com
Country
China
ProdList
9779
Advantage
58
Zhengzhou Akem Chemical Co., Ltd
Tel
13303867194
Email
3001317055@qq.com
Country
China
ProdList
9801
Advantage
58
Tianjin Kaimu Chemical Technology Co., LTD
Tel
13116033142 13116033142
Email
kaimuchem@163.com
Country
China
ProdList
862
Advantage
58
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View Lastest Price from DBCO-PEG9-amine manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.
Product
DBCO-PEG9-NH2 2353409-99-9
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
1g/bottle, 10g/bottle, 100g/bottle
Release date
2026-02-06
Xian confluore Biological Technology Co., Ltd.
Product
DBCO-PEG9-amine 2353409-99-9
Price
US $0.00/mg
Min. Order
50mg
Purity
>97.00%
Supply Ability
250
Release date
2024-03-20

2353409-99-9, DBCO-PEG9-amineRelated Search:


  • DBCO-PEG9-amine
  • DBCO-PEG9-amine TFA salt
  • Dibenz[b,f]azocine-5(6H)-butanamide, N-(29-amino-3,6,9,12,15,18,21,24,27-nonaoxanonacos-1-yl)-11,12-didehydro-γ-oxo-
  • DBCO-PEG9-NH2
  • 2353409-99-9