Fmoc-PEG3-CH2CO2-NHS

Product Name: Fmoc-PEG3-CH2CO2-NHS
CAS No.: 2128735-25-9
Chemical Name: Fmoc-PEG3-CH2CO2-NHS
Synonyms: Fmoc-PEG3-CH2CO2-NHS;FmocNH-PEG3-CH2COONHS;Fmoc-N-PEG3-CH2-NHS ester;5,8,11-Trioxa-2-azatridecanedioic acid, 13-(2,5-dioxo-1-pyrrolidinyl) 1-(9H-fluoren-9-ylmethyl) ester;FmocNH-PEG3-CH2COONHS/5,8,11-Trioxa-2-azatridecanedioic acid, 13-(2,5-dioxo-1-pyrrolidinyl) 1-(9H-fluoren-9-ylmethyl) ester
CBNumber: CB74849596
Molecular Formula: C27H30N2O9
Formula Weight: 526.54
MOL File: 2128735-25-9.mol

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Fmoc-PEG3-CH2CO2-NHS Property

Density: 1.35±0.1 g/cm3(Predicted)
solubility: Soluble in DMSO, DCM, DMF
pka: 11.60±0.46(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23791
Product name: Fmoc-PEG3-CH2CO2-NHS
Purity: 98%
Packaging: 250mg
Price: $280
Updated: 2021/12/16

BroadPharm

Product number: BP-23791
Product name: Fmoc-PEG3-CH2CO2-NHS
Purity: 98%
Packaging: 500mg
Price: $430
Updated: 2021/12/16

Activate Scientific

Product number: AS107923
Product name: FmocNH-PEG3-CH2COONHS
Purity: 97%
Packaging: 1g
Price: $515
Updated: 2021/12/16

BroadPharm

Product number: BP-23791
Product name: Fmoc-PEG3-CH2CO2-NHS
Purity: 98%
Packaging: 1g
Price: $680
Updated: 2021/12/16

Acrotein

Product number: B-1461
Product name: FmocNH-PEG3-CH2COONHS
Purity: 97%
Packaging: 1g
Price: $366.67
Updated: 2021/12/16

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Fmoc-PEG3-CH2CO2-NHS Chemical Properties,Usage,Production

Description

Fmoc-PEG3-CH2CO2-NHS is a PEG linker containing an Fmoc group and an NHS ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations.

Uses

Fmoc-N-PEG3-CH2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Fmoc-PEG3-CH2CO2-NHS Preparation Products And Raw materials

Raw materials

Preparation Products

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Fmoc-PEG3-CH2CO2-NHS Suppliers

China 14 United States 3 Global 17

Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Fax: 0512-56316826
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Country: China
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TargetMol Chemicals Inc.

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Shaanxi Xinyan Bomei Biotechnology Co., Ltd.

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Shaanxi borno biotechnology co., LTD

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Zhengzhou Akem Chemical Co., Ltd

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Beijing Jin Ming Biotechnology Co., Ltd.

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Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

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Shanghai Easy CDMO Co.,Ltd

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Shanghai Zhiyun Biotechnology Co., Ltd

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Jilin Chinese Academy of Sciences-yanshen Technology

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2128735-25-9, Fmoc-PEG3-CH2CO2-NHSRelated Search:

Fmoc-PEG3-CH2CO2-NHS

FmocNH-PEG3-CH2COONHS

Fmoc-N-PEG3-CH2-NHS ester

FmocNH-PEG3-CH2COONHS/5,8,11-Trioxa-2-azatridecanedioic acid, 13-(2,5-dioxo-1-pyrrolidinyl) 1-(9H-fluoren-9-ylmethyl) ester

5,8,11-Trioxa-2-azatridecanedioic acid, 13-(2,5-dioxo-1-pyrrolidinyl) 1-(9H-fluoren-9-ylmethyl) ester

2128735-25-9