AWZ1066S

Product Name: AWZ1066S
CAS No.: 2239272-16-1
Chemical Name: AWZ1066S
Synonyms: AWZ1066S;AWZ1066S;AWZ-1066S;AWZ 1066S;2-[(3S)-3-methylmorpholin-4-yl]-N-{[2-(trifluoromethyl)pyridin-3-yl]methyl}pyrido[2,3-d]pyrimidin-4-amine;2-[(3S)-3-Methyl-4-morpholinyl]-N-[[2-(trifluoromethyl)-3-pyridinyl]methyl]pyrido[2,3-d]pyrimidin-4-amine;Pyrido[2,3-d]pyrimidin-4-amine, 2-[(3S)-3-methyl-4-morpholinyl]-N-[[2-(trifluoromethyl)-3-pyridinyl]methyl]-;oral,Inhibitor,anti-Wolbachia,Onchocerciasis (river blindness),CYP3A4,AWZ1066S,Parasite,AWZ-1066S,CYP2C9,tropical diseases,inhibit,lymphatic filariasis (elephantiasis)
CBNumber: CB74857313
Molecular Formula: C19H19F3N6O
Formula Weight: 404.39
MOL File: 2239272-16-1.mol

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AWZ1066S Property

storage temp.: Store at -20°C
solubility: DMSO : 125 mg/mL (309.11 mM; Need ultrasonic)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0084989
Product name: AWZ1066S
Purity: 98.65%
Packaging: 5mg
Price: $205
Updated: 2021/12/16

ChemScene

Product number: CS-0084989
Product name: AWZ1066S
Purity: 98.65%
Packaging: 10mg
Price: $350
Updated: 2021/12/16

ChemScene

Product number: CS-0084989
Product name: AWZ1066S
Purity: 98.65%
Packaging: 50mg
Price: $850
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb573421
Product name: AWZ1066S
Purity: >98%
Packaging: 50mg
Price: $1283.5
Updated: 2021/12/16

ChemScene

Product number: CS-0084989
Product name: AWZ1066S
Purity: 98.65%
Packaging: 100mg
Price: $1450
Updated: 2021/12/16

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AWZ1066S Chemical Properties,Usage,Production

Biological Activity

AWZ1066S is a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis, with an EC50 of 2.5 nM in cell assay[1].

References

[1]. Hong WD, et al. AWZ1066S, a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis. Proc Natl Acad Sci U S A. 2019 Jan 22;116(4):1414-1419.

AWZ1066S Preparation Products And Raw materials

Raw materials

Preparation Products

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AWZ1066S Suppliers

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2239272-16-1, AWZ1066SRelated Search:

AWZ1066S

AWZ1066S;AWZ-1066S;AWZ 1066S

Pyrido[2,3-d]pyrimidin-4-amine, 2-[(3S)-3-methyl-4-morpholinyl]-N-[[2-(trifluoromethyl)-3-pyridinyl]methyl]-

2-[(3S)-3-Methyl-4-morpholinyl]-N-[[2-(trifluoromethyl)-3-pyridinyl]methyl]pyrido[2,3-d]pyrimidin-4-amine

oral,Inhibitor,anti-Wolbachia,Onchocerciasis (river blindness),CYP3A4,AWZ1066S,Parasite,AWZ-1066S,CYP2C9,tropical diseases,inhibit,lymphatic filariasis (elephantiasis)

2-[(3S)-3-methylmorpholin-4-yl]-N-{[2-(trifluoromethyl)pyridin-3-yl]methyl}pyrido[2,3-d]pyrimidin-4-amine

2239272-16-1

239272-16-1