STING agonist-3

Product Name: STING agonist-3
CAS No.: 2138299-29-1
Chemical Name: STING agonist-3
Synonyms: STING agonist-3;diABZI STING Agonist-3;STING agonist compound 3;STING agonist 3,STING agonist3;Kynurenic Acid Impurity 5(Quinclorac);1-[(2E)-4-[5-carbamoyl-2-(1-ethyl-3-methyl-1H-pyrazole-5-amido)-1H-1,3-benzodiazol-1-yl]but-2-en-1-yl]-2-(1-ethyl-3-methyl-1H-pyrazole-5-amido)-7-(3-hydroxypropoxy)-1H-1,3-benzodiazole-5-carboxamide;(E)-1-(4-(5-Carbamoyl-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-1H-benzo[d]imidazol-1-yl)but-2-en-1-yl)-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-(3-hydroxypropoxy)-1H-benzo[d]imidazole-5-carboxamide;1H-Benzimidazole-5-carboxamide, 1-[(2E)-4-[5-(aminocarbonyl)-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-1H-benzimidazol-1-yl]-2-buten-1-yl]-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-7-(3-hydroxypropoxy)-;1H-Benzimidazole-5-carboxamide, 1-[(2E)-4-[5-(aminocarbonyl)-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-1H-benzimidazol-1-yl]-2-buten-1-yl]-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-7-(3-hydroxypropoxy)- (ACI)
CBNumber: CB74868676
Molecular Formula: C37H42N12O6
Formula Weight: 750.81
MOL File: 2138299-29-1.mol

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STING agonist-3 Property

Density: 1.47±0.1 g/cm3(Predicted)
solubility: DMSO: 40 mg/ml, sonicated
form: A solid
pka: 11.86±0.43(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0029879
Product name: STINGagonist-3
Purity: 99.96%
Packaging: 5mg
Price: $400
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb573123
Product name: STING agonist compound 3
Purity: >98%
Packaging: 5mg
Price: $690.2
Updated: 2021/12/16

ChemScene

Product number: CS-0029879
Product name: STINGagonist-3
Purity: 99.96%
Packaging: 10mg
Price: $700
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb573123
Product name: STING agonist compound 3
Purity: >98%
Packaging: 10mg
Price: $1060.8
Updated: 2021/12/16

ChemScene

Product number: CS-0029879
Product name: STINGagonist-3
Purity: 99.96%
Packaging: 25mg
Price: $1100
Updated: 2021/12/16

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STING agonist-3 Chemical Properties,Usage,Production

Uses

STING agonist-3, extracted from patent WO2017175147A1 (example 10), is a selective and non-nucleotide small-molecule?STING?agonist with a pEC50 and pIC50 of 7.5 and 9.5, respectively. STING agonist-3 has durable anti-tumor effect and tremendous potential to improve treatment of cancer[1].

References

[1] Adam Kenneth, et al. Heterocyclic amides useful as protein modulators.patent WO2017175147A1
[2] Ramanjulu JM, Pesiridis GS, Yang J, et al. Design of amidobenzimidazole STING receptor agonists with systemic activity [published correction appears in Nature. 2019 Jun;570(7761):E53. doi: 10.1038/s41586-019-1265-5]. Nature. 2018;564(7736):439-443. DOI:10.1038/s41586-018-0705-y

STING agonist-3 Preparation Products And Raw materials

Raw materials

Preparation Products

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STING agonist-3 Suppliers

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View Lastest Price from STING agonist-3 manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: STING agonist-3 2138299-29-1
Price: US $2.00-5.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-06-24

2138299-29-1, STING agonist-3Related Search:

1H-Benzimidazole-5-carboxamide, 1-[(2E)-4-[5-(aminocarbonyl)-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-7-methoxy-1H-benzimidazol-1-yl]-2-buten-1-yl]-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-7-[3-(4-morpholinyl)propoxy]- N-(dibenzo[b,d]furan-3-yl)-5-nitrofuran-2-carboxamide

STING agonist-3

STING agonist compound 3

1H-Benzimidazole-5-carboxamide, 1-[(2E)-4-[5-(aminocarbonyl)-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-1H-benzimidazol-1-yl]-2-buten-1-yl]-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-7-(3-hydroxypropoxy)-

STING agonist 3,STING agonist3

diABZI STING Agonist-3

1H-Benzimidazole-5-carboxamide, 1-[(2E)-4-[5-(aminocarbonyl)-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-1H-benzimidazol-1-yl]-2-buten-1-yl]-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-7-(3-hydroxypropoxy)- (ACI)

Kynurenic Acid Impurity 5(Quinclorac)

(E)-1-(4-(5-Carbamoyl-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-1H-benzo[d]imidazol-1-yl)but-2-en-1-yl)-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-(3-hydroxypropoxy)-1H-benzo[d]imidazole-5-carboxamide

1-[(2E)-4-[5-carbamoyl-2-(1-ethyl-3-methyl-1H-pyrazole-5-amido)-1H-1,3-benzodiazol-1-yl]but-2-en-1-yl]-2-(1-ethyl-3-methyl-1H-pyrazole-5-amido)-7-(3-hydroxypropoxy)-1H-1,3-benzodiazole-5-carboxamide

2138299-29-1

C37H42N12O6