2-(2-BROMOACETYL)THIOPHENE

Product Name: 2-(2-BROMOACETYL)THIOPHENE
CAS No.: 10531-41-6
Chemical Name: 2-(2-BROMOACETYL)THIOPHENE
Synonyms: TIMTEC-BB SBB005904;2-(2-BROMOACETYL)THIOPHENE;2-(Bromoacetyl)thiophene97%;2-(Bromoacetyl)thiophene 97%;2-(2-Bromoethyl)Thiophene98%;2-(2-Bromoacetyl)thiophene97%;2-bromo-1-(2-thienyl)ethanone;2-BROMO-1-(2-THIENYL)-1-ETHANONE;Ethanone, 2-bromo-1-(2-thienyl)-;2-Bromo-1-(thien-2-yl)ethan-1-one
CBNumber: CB7488065
Molecular Formula: C6H5BrOS
Formula Weight: 205.07
MOL File: 10531-41-6.mol

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2-(2-BROMOACETYL)THIOPHENE Property

Melting point:: 29-33 °C(lit.)
Boiling point:: 100-105°C 0,5mm
Density: 1.62
Flash point:: >230 °F
storage temp.: -20°C
form: crystalline needles
color: Off white/cream
Sensitive: Stench
CAS DataBase Reference: 10531-41-6(CAS DataBase Reference)

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Safety

Hazard Codes: C,T
Risk Statements: 22-34-43
Safety Statements: 26-36/37/39-45
RIDADR: UN 3261 8/PG 2
WGK Germany: 3
Hazard Note: Keep Cold/Toxic/Stench
HazardClass: 8
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 595594
Product name: 2-(2-Bromoacetyl)thiophene
Purity: 97%
Packaging: 1g
Price: $108
Updated: 2025/07/31

Sigma-Aldrich

Product number: 595594
Product name: 2-(2-Bromoacetyl)thiophene
Purity: 97%
Packaging: 5g
Price: $291.9
Updated: 2025/07/31

TCI Chemical

Product number: B5383
Product name: 2-(Bromoacetyl)thiophene
Purity: min. 95.0 %
Packaging: 1G
Price: $90
Updated: 2025/07/31

TCI Chemical

Product number: B5383
Product name: 2-(Bromoacetyl)thiophene
Purity: min. 95.0 %
Packaging: 5G
Price: $270
Updated: 2025/07/31

TRC

Product number: B679378
Product name: 2-(2-Bromoacetyl)thiophene
Packaging: 1g
Price: $75
Updated: 2021/12/16

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2-(2-BROMOACETYL)THIOPHENE Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Synthesis

88-15-3

10531-41-6

Example 1.12: Synthesis of 2-bromo-1-(thiophen-2-yl)ethan-1-one. A solution of bromine (2.53 g, 0.82 mL, 0.0158 mol) in dichloromethane (8 mL) was added dropwise to a solution of 2-acetylthiophene (2.0 g, 1.71 mL, 0.0158 mol) in dichloromethane (10 mL). The reaction mixture was stirred at 25 °C for 1 h and subsequently neutralized with saturated aqueous sodium bicarbonate solution. The organic layer was washed with water and dried. After evaporation of the solvent, the solid residue was purified by column chromatography (silica gel, eluent ethyl acetate:n-hexane = 5:95) to afford 2-bromo-1-(thiophen-2-yl)ethan-1-one as an oil (2.60 g, 80% yield). [Note: Alternative preparations of 1-(thiophen-2-yl)ethan-1-one have been reported recently, see: Ostrowski, T.; Golankiewicz, B.; De Clercq, E.; Andrei, G.; Snoeck, R. Synthesis and anti-VZV activity of tricyclic acyclovir and 9-{[cis-1',2'-bis(hydroxymethyl)cycloprop-1'-yl]methyl}guanine analogues as 6-heteroaryl derivatives. eur. J. Med. Chem. 2009, 44, 3313-3317.]

References

[1] Phosphorus and Sulfur and the Related Elements, 1988, vol. 40, p. 243 - 250
[2] Synthetic Communications, 1996, vol. 26, # 6, p. 1083 - 1096
[3] Russian Journal of Organic Chemistry, 2001, vol. 37, # 9, p. 1210 - 1219
[4] ChemMedChem, 2018, vol. 13, # 11, p. 1102 - 1114
[5] Phosphorus, Sulfur and Silicon and the Related Elements, 2013, vol. 188, # 12, p. 1835 - 1844

2-(2-BROMOACETYL)THIOPHENE Preparation Products And Raw materials

Raw materials

2-Acetylthiophene Carbon tetrachloride Bromine Iron

Preparation Products

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2-(2-BROMOACETYL)THIOPHENE Suppliers

Americas 1 Belgium 1 China 112 Europe 4 Germany 3 India 3 Japan 1 Switzerland 1 United Kingdom 3 United States 17 Global 146

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View Lastest Price from 2-(2-BROMOACETYL)THIOPHENE manufacturers

Career Henan Chemical Co

Product: 2-(2-BROMOACETYL)THIOPHENE 10531-41-6
Price: US $9.80/KG
Min. Order: 1g
Purity: ≥99%
Supply Ability: 100kg
Release date: 2020-01-08

10531-41-6, 2-(2-BROMOACETYL)THIOPHENERelated Search:

2-BROMO-1-[5-(2-PYRIDINYL)-2-THIENYL]-1-ETHANONE 2-BROMO-1-(5-BROMOTHIOPHEN-2-YL)ETHANONE 2-(2-BROMOACETYL)THIOPHENE 2-BROMO-1-(5-PHENYL-2-THIENYL)-1-ETHANONE 2-BROMO-1-(5-CHLORO-3-METHYLBENZO[B]THIOPHEN-2-YL)ETHAN-1-ONE 5-(bromoacetyl)thiophene-2-carbonitrile,5-(2-Bromoacetyl)thiophene-2-carbonitrile 1-(1-BENZOTHIOPHEN-2-YL)-2-BROMO-1-ETHANONE 5-(BROMOACETYL)THIOPHENE-2-CARBOXAMIDE 2-BROMO-1-(5-CHLORO-3-METHYLBENZO[B]THIOPHEN-2-YL)ETHAN-1-ONE 2-BROMO-1-(2-THIENYL)-1-PROPANONE 2-BROMO-1-(5-CHLORO-THIOPHEN-2-YL)-ETHANONE 2-BROMO-1-(3-CHLORO-2-THIENYL)-1-ETHANONE 2-BROMO-1-(3-BROMO-2-THIENYL)-1-ETHANONE 2-BROMO-1-(3,5-DIMETHYL-1-BENZOTHIOPHEN-2-YL)-1-ETHANONE N-(5-BROMO-6-OXO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHEN-4-YL)-2,2,2-TRIFLUOROACETAMIDE 3-BROMO-4-OXO-4-THIEN-2-YLBUTANOIC ACID 2,2-DIBROMO-1-THIEN-2-YLETHANONE 2,2-DIBROMO-1-(5-BROMO-2-THIENYL)ETHAN-1-ONE

2-Bromo-1-(2-thienyl)-1-ethanone, Tech.

2-(Bromoacetyl)thiophene 97%

2-Bromo-1-(thien-2-yl)ethan-1-one

2-broMo-1-(thiophen-2-yl)ethan-1-one

2-broMo-1-(thiophen-2-yl)-1-ethanone

2-Bromo-1-(thien-2-yl)ethan-1-one, 2-(2-Bromoethanoyl)thiophene

2-(Bromoacetyl)thiophene97%

TIMTEC-BB SBB005904

2-(2-BROMOACETYL)THIOPHENE

2-BROMO-1-(2-THIENYL)-1-ETHANONE

2-(2-Bromoacetyl)thiophene97%

2-bromo-1-(2-thienyl)ethanone

Ethanone, 2-bromo-1-(2-thienyl)-

2-(2-Bromoethyl)Thiophene98%

Ethanone, 2-bromo-1-(2-thienyl)- (9CI)

2-(2-BROMOACETYL)THIOPHENE ISO 9001：2015 REACH

2(1H)-Pyridinone,5,6-dihydro-3-(4-morpholinyl)-1-[4-(2-oxo-4-piperidinyl)phenyl]-

10531-41-6

Halogenated Heterocycles

Heterocyclic Building Blocks

Acetyl Halides

Thiophenes & Benzothiophenes

Halogenated Heterocycles

Heterocyclic Building Blocks

Thiophenes

ThiophenesBuilding Blocks

Acetyl Halides

Thiophenes & Benzothiophenes

ACETYLHALIDE

Building Blocks

C4 to C6

Chemical Synthesis