ChemicalBook > CAS DataBase List > 9,15-DIOXO-11ALPHA-HYDROXY-2,3,4,5-TETRANOR-PROSTAN-1,20-DIOIC ACID

9,15-DIOXO-11ALPHA-HYDROXY-2,3,4,5-TETRANOR-PROSTAN-1,20-DIOIC ACID

Product Name
9,15-DIOXO-11ALPHA-HYDROXY-2,3,4,5-TETRANOR-PROSTAN-1,20-DIOIC ACID
CAS No.
24769-56-0
Chemical Name
9,15-DIOXO-11ALPHA-HYDROXY-2,3,4,5-TETRANOR-PROSTAN-1,20-DIOIC ACID
Synonyms
TETRANOR-PGEM;Tetranor-PGEM-13C6;prostaglandin E2-UM;TETRANOR PROSTAGLANDIN E METABOLITE;tetranor-PGEM Lipid Maps MS Standard;9,15-DIOXO-11ALPHA-HYDROXY-2,3,4,5-TETRANOR-PROSTAN-1,20-DIOIC ACID;11alpha-hydroxy-9,15-dioxo-2,3,4,5,20-pentanor-19-carboxyprostanoicacid;Cyclopentaneoctanoic acid, 2-(2-carboxyethyl)-5-hydroxy-ε,3-dioxo-, (1R,2R,5R)-
CBNumber
CB7492637
Molecular Formula
C16H24O7
Formula Weight
328.36
MOL File
24769-56-0.mol
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9,15-DIOXO-11ALPHA-HYDROXY-2,3,4,5-TETRANOR-PROSTAN-1,20-DIOIC ACID Property

Boiling point:
622.2±50.0 °C(Predicted)
Density 
1.266±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: Not Stable; PBS (pH 7.2): 1 mg/ml
form 
Liquid
pka
4.61±0.10(Predicted)
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

H336May cause drowsiness or dizziness

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
14840
Product name
tetranor-PGEM
Purity
≥98%
Packaging
25μg
Price
$133
Updated
2024/03/01
Cayman Chemical
Product number
14840
Product name
tetranor-PGEM
Purity
≥98%
Packaging
50μg
Price
$251
Updated
2024/03/01
Cayman Chemical
Product number
14840
Product name
tetranor-PGEM
Purity
≥98%
Packaging
100μg
Price
$474
Updated
2024/03/01
TRC
Product number
P294100
Product name
PGE-M
Packaging
25mg
Price
$16225
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CCH0039105
Product name
9,15-DIOXO-11ALPHA-HYDROXY-13,14-DIHYDRO-2,3,4,5-TETRANOR-PROSTAN-1,20-DIOIC ACID
Purity
95.00%
Packaging
5MG
Price
$504.52
Updated
2021/12/16
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9,15-DIOXO-11ALPHA-HYDROXY-2,3,4,5-TETRANOR-PROSTAN-1,20-DIOIC ACID Chemical Properties,Usage,Production

Description

tetranor-PGEM is the major urinary metabolite of PGE1 and PGE2, and is used as a marker of PGE2 biosynthesis. About 15% of an infused dose of PGE2 appears as this metabolite in the urine of humans. Normal healthy males excrete 7-40 μg of tetranor-PGEM over a 24-hour period.

Uses

The major urinary metabolite of Prostaglandin E2 (P838610).

Definition

ChEBI: A prostanoid that is prostaglandin E2 in which the acyclic hydroxy group has been oxidised to the corresponding ketone, the methyl group has been oxidised to the corresponding carboxylic acid and the 6-carboxyhexenyl group has been oxidatively cleaved to a 2-carboxyethyl group. It is the major urinary metabolite of prostaglandin E2.

9,15-DIOXO-11ALPHA-HYDROXY-2,3,4,5-TETRANOR-PROSTAN-1,20-DIOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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9,15-DIOXO-11ALPHA-HYDROXY-2,3,4,5-TETRANOR-PROSTAN-1,20-DIOIC ACID Suppliers

J & K SCIENTIFIC LTD.
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24769-56-0, 9,15-DIOXO-11ALPHA-HYDROXY-2,3,4,5-TETRANOR-PROSTAN-1,20-DIOIC ACIDRelated Search:


  • 11alpha-hydroxy-9,15-dioxo-2,3,4,5,20-pentanor-19-carboxyprostanoicacid
  • 9,15-DIOXO-11ALPHA-HYDROXY-2,3,4,5-TETRANOR-PROSTAN-1,20-DIOIC ACID
  • TETRANOR PROSTAGLANDIN E METABOLITE
  • TETRANOR-PGEM
  • tetranor-PGEM Lipid Maps MS Standard
  • prostaglandin E2-UM
  • Cyclopentaneoctanoic acid, 2-(2-carboxyethyl)-5-hydroxy-ε,3-dioxo-, (1R,2R,5R)-
  • Tetranor-PGEM-13C6
  • 24769-56-0
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals