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Cav 2.2 blocker 1

Product Name
Cav 2.2 blocker 1
CAS No.
1567335-29-8
Chemical Name
Cav 2.2 blocker 1
Synonyms
Cav 2.2 blocker 1;Cav 2.2 blocker 1 ,S0000;Cav 2.2 blocker 1, 10 mM in DMSO;Ca2+ channels,Inhibitor,inhibit,Cav 2.2 blocker 1,Ca channels,Calcium Channel;5-(4-Chlorophenyl)-1-(2-methoxyphenyl)-3-(2,2,6,6-tetramethyltetrahydro-2H-pyran-4-yl)-1H-pyrazole;1H-Pyrazole, 5-(4-chlorophenyl)-1-(2-methoxyphenyl)-3-(tetrahydro-2,2,6,6-tetramethyl-2H-pyran-4-yl)-
CBNumber
CB74927535
Molecular Formula
C25H29ClN2O2
Formula Weight
424.96
MOL File
1567335-29-8.mol
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Cav 2.2 blocker 1 Property

Boiling point:
547.2±50.0 °C(Predicted)
Density 
1.16±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: 20.83 mg/mL (49.02 mM)
pka
-0.67±0.10(Predicted)
form 
Solid
color 
Off-white to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0067941
Product name
Cav2.2blocker1
Purity
99.30%
Packaging
5mg
Price
$350
Updated
2021/12/16
ChemScene
Product number
CS-0067941
Product name
Cav2.2blocker1
Purity
99.30%
Packaging
10mg
Price
$550
Updated
2021/12/16
ChemScene
Product number
CS-0067941
Product name
Cav2.2blocker1
Purity
99.30%
Packaging
50mg
Price
$1650
Updated
2021/12/16
ChemScene
Product number
CS-0067941
Product name
Cav2.2blocker1
Purity
99.30%
Packaging
100mg
Price
$2650
Updated
2021/12/16
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Cav 2.2 blocker 1 Chemical Properties,Usage,Production

Uses

Cav 2.2 blocker 1 (compound 9) is a N-type calcium channel (Cav 2.2) blocker for the treatment of pain, with an IC50 of 1 nM[1].

References

[1] Wall MJ, et al. Discovery and optimization of a novel series of pyrazolyltetrahydropyran N-type calcium channel (Cav 2.2) blockers for the treatment of pain. Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3780-3783. DOI:10.1016/j.bmcl.2018.10.007

Cav 2.2 blocker 1 Preparation Products And Raw materials

Raw materials

Preparation Products

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Cav 2.2 blocker 1 Suppliers

BOC Sciences
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1567335-29-8, Cav 2.2 blocker 1Related Search:


  • Cav 2.2 blocker 1
  • 1H-Pyrazole, 5-(4-chlorophenyl)-1-(2-methoxyphenyl)-3-(tetrahydro-2,2,6,6-tetramethyl-2H-pyran-4-yl)-
  • Ca2+ channels,Inhibitor,inhibit,Cav 2.2 blocker 1,Ca channels,Calcium Channel
  • 5-(4-Chlorophenyl)-1-(2-methoxyphenyl)-3-(2,2,6,6-tetramethyltetrahydro-2H-pyran-4-yl)-1H-pyrazole
  • Cav 2.2 blocker 1, 10 mM in DMSO
  • Cav 2.2 blocker 1 ,S0000
  • 1567335-29-8