ChemicalBook > CAS DataBase List > L-2-AMINO-5-PHENYL-PENTANOIC ACID

L-2-AMINO-5-PHENYL-PENTANOIC ACID

Product Name
L-2-AMINO-5-PHENYL-PENTANOIC ACID
CAS No.
62777-25-7
Chemical Name
L-2-AMINO-5-PHENYL-PENTANOIC ACID
Synonyms
L-PEA;L-Nva(5-phenyl)-OH;H-NVA(5-PHENYL)-OH;(S)-2-Amino-5-phenylpentanoicaci;(S)-2-amino-4-phenylvaleric acid;L-2-AMINO-5-PHENYL-PENTANOIC ACID;(2S)-2-amino-5-phenylpentanoic acid;Benzenepentanoic acid, α-amino-, (αS)-;L-2-AMINO-5-PHENYL-PENTANOIC ACID USP/EP/BP
CBNumber
CB7492899
Molecular Formula
C11H15NO2
Formula Weight
193.24
MOL File
62777-25-7.mol
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L-2-AMINO-5-PHENYL-PENTANOIC ACID Property

Melting point:
228-230 °C
Boiling point:
375.2±42.0 °C(Predicted)
Density 
1.133±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Acetic Acid (Slightly, Heated, Sonicated), Aqueous Base (Slightly)
form 
Solid
pka
2.52±0.24(Predicted)
color 
White to Off-White
optical activity
1.9°(C=0.01g/mI, H2O, 20°C, 589nm)
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
A615840
Product name
L-2-Amino-5-phenyl-pentanoicacid
Packaging
50mg
Price
$55
Updated
2021/12/16
Usbiological
Product number
453119
Product name
L-2-Amino-5-phenyl-pentanoic acid
Packaging
25mg
Price
$305
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
38254
Product name
H-Nva(5-phenyl)-OH
Packaging
1g
Price
$365
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA50358
Product name
L-2-Amino-5-phenylpentanoic acid
Packaging
2g
Price
$401.1
Updated
2021/12/16
Activate Scientific
Product number
AS85896
Product name
(S)-2-Amino-5-phenyl-pentanoic acid
Purity
95+% ee
Packaging
5G
Price
$592
Updated
2021/12/16
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L-2-AMINO-5-PHENYL-PENTANOIC ACID Chemical Properties,Usage,Production

Synthesis

52161-76-9

62777-25-7

L-styrylalanine (CAS: 52161-76-9, 50 mg, 0.26 mmol) was used as starting material, which was dissolved in methanol (5 mL) and the reaction vessel was flushed with nitrogen. Subsequently, a catalytic amount of 10% palladium/carbon catalyst was added. The reaction vessel was placed under hydrogen atmosphere and the reaction mixture was stirred at room temperature for 2 hours. Upon completion of the reaction, the catalyst was filtered through diatomaceous earth to remove the catalyst. The filtrate was concentrated under reduced pressure to remove the organic solvent to afford the target product (S)-2-amino-5-phenylpentanoic acid (51 mg, quantitative yield) as a white powder. The structure of the product was confirmed by 1H-NMR (400 MHz, CD3OD): δ= 7.42-7.25 (m, 5H), 3.71 (t, J = 6.0 Hz, 1H), 2.69 (t, J = 6.4 Hz, 2H), 1.85 (m, 2H), 1.70 (m, 2H). Mass spectrometry result: C11H16NO2 ([M+H]+) calculated value 194.12, measured value 194.4.

References

[1] Patent: US2004/198780, 2004, A1. Location in patent: Page 23

L-2-AMINO-5-PHENYL-PENTANOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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L-2-AMINO-5-PHENYL-PENTANOIC ACID Suppliers

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