2-(2,4-DIFLUOROPHENYL)PYRIDINE
- Product Name
- 2-(2,4-DIFLUOROPHENYL)PYRIDINE
- CAS No.
- 391604-55-0
- Chemical Name
- 2-(2,4-DIFLUOROPHENYL)PYRIDINE
- Synonyms
- CAS:391604-55-0;2-(2,4-Difluorophenyl)pyridine;Pyridine, 2-(2,4-difluorophenyl)-;2-(2,4-Difluorophenyl)pyridine>2-(2,4-Difluorophenyl)pyridine 97%;2-(2,4-Difluorophenyl)pyridine, min. 97%;2-(2,4-DIFLUOROPHENYL)PYRIDINE ISO 9001:2015 REACH
- CBNumber
- CB7505807
- Molecular Formula
- C11H7F2N
- Formula Weight
- 191.18
- MOL File
- 391604-55-0.mol
2-(2,4-DIFLUOROPHENYL)PYRIDINE Property
- Density
- 1.254 g/mL at 25 °C
- refractive index
- n20/D1.570
- Flash point:
- 103℃
- storage temp.
- Inert atmosphere,Room Temperature
- form
- crystal
- pka
- 3.91±0.25(Predicted)
- color
- white
- Boiling point:
- 95°C/0.4 mmHg
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-37/38-41-36/37/38
- Safety Statements
- 26-39-24/25
- WGK Germany
- 3
- TSCA
- No
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- 667676
- Product name
- 2-(2,4-Difluorophenyl)pyridine
- Purity
- 97%
- Packaging
- 1g
- Price
- $64.48
- Updated
- 2025/07/31
- Product number
- D3413
- Product name
- 2-(2,4-Difluorophenyl)pyridine
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $37
- Updated
- 2025/07/31
- Product number
- D3413
- Product name
- 2-(2,4-Difluorophenyl)pyridine
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $146
- Updated
- 2025/07/31
- Product number
- 07-1420
- Product name
- 2-(2,4-Difluorophenyl)pyridine, min. 97%
- Purity
- min. 97%
- Packaging
- 1g
- Price
- $56
- Updated
- 2024/03/01
- Product number
- 07-1420
- Product name
- 2-(2,4-Difluorophenyl)pyridine, min. 97%
- Purity
- min. 97%
- Packaging
- 5g
- Price
- $217
- Updated
- 2024/03/01
2-(2,4-DIFLUOROPHENYL)PYRIDINE Chemical Properties,Usage,Production
Chemical Properties
Colorless to dark yellow liquid
Uses
Ligand used in a blue-light emitting Ir(III) complexes suitable for use as phosphorescent OLEDs.
Synthesis
109-04-6
144025-03-6
391604-55-0
General procedure for the synthesis of 2-(2,4-difluorophenyl)pyridine from 2-bromopyridine and 2,4-difluorophenylboronic acid: 2-bromopyridine (2.01 mL, 21.1 mmol), 2,4-difluorophenylboronic acid (4.00 g, 25.3 mmol), and tetrakis(triphenylphosphine)palladium(0) (0.732 g, 0.633 mmol) were added to a reflux condenser equipped with a round bottom flask and dissolved in 50 mL of tetrahydrofuran (THF). Subsequently, 30 mL of 2 M sodium carbonate (Na2CO3) aqueous solution was added to the reaction system. The reaction mixture was heated to reflux at 70°C for 24 hours. After completion of the reaction, it was cooled to room temperature and the crude reaction mixture was poured into water and extracted with dichloromethane (CH2Cl2, 50 mL x 3). The organic phases were combined and dried with anhydrous magnesium sulfate. Purification by silica gel column chromatography (eluent: n-hexane/ethyl acetate=4:1, v/v) afforded the target product 2-(2,4-difluorophenyl)pyridine (dfppy 1) as a colorless liquid (3.90 g, 97% yield).
References
[1] Journal of the American Chemical Society, 2005, vol. 127, # 36, p. 12438 - 12439
[2] Inorganic Chemistry, 2017, vol. 56, # 19, p. 11565 - 11576
[3] Patent: US2012/273765, 2012, A1. Location in patent: Page/Page column 23-24
[4] Chemical Science, 2016, vol. 8, # 1, p. 348 - 360
[5] Patent: US2006/237715, 2006, A1. Location in patent: Page/Page column 11; 13
2-(2,4-DIFLUOROPHENYL)PYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-(2,4-DIFLUOROPHENYL)PYRIDINE manufacturers
- Product
- 2-(2,4-Difluorophenyl)pyridine 391604-55-0
- Price
- US $188.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%, 99.5% Sublimated
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-01-05
- Product
- 2-(2,4-DIFLUOROPHENYL)PYRIDINE 391604-55-0
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-10-27
- Product
- 2-(2,4-DIFLUOROPHENYL)PYRIDINE 391604-55-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- Customized
- Release date
- 2018-08-08