Benzamide, 3-methoxy-N-[4-(4-methoxyphenyl)-2-thiazolyl]-4-[2-(4-morpholinyl)-2-oxoethoxy]-

Product Name: Benzamide, 3-methoxy-N-[4-(4-methoxyphenyl)-2-thiazolyl]-4-[2-(4-morpholinyl)-2-oxoethoxy]-
CAS No.: 781628-99-7
Chemical Name: Benzamide, 3-methoxy-N-[4-(4-methoxyphenyl)-2-thiazolyl]-4-[2-(4-morpholinyl)-2-oxoethoxy]-
Synonyms: SBI-477, 10 mM in DMSO;Inhibitor,SBI-477,inhibit,SBI 477,SBI477;3-Methoxy-N-(4-(4-methoxyphenyl)thiazol-2-yl)-4-(2-morpholino-2-oxoethoxy)benzamide;Benzamide, 3-methoxy-N-[4-(4-methoxyphenyl)-2-thiazolyl]-4-[2-(4-morpholinyl)-2-oxoethoxy]-
CBNumber: CB75490401
Molecular Formula: C24H25N3O6S
Formula Weight: 483.54
MOL File: 781628-99-7.mol

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Benzamide, 3-methoxy-N-[4-(4-methoxyphenyl)-2-thiazolyl]-4-[2-(4-morpholinyl)-2-oxoethoxy]- Property

Density: 1.331±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: 65 mg/mL (134.43 mM)
form: Solid
pka: 7.14±0.50(Predicted)
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

DC Chemicals

Product number: DC21625
Product name: SBI-477
Purity: >98%
Packaging: 100mg
Price: $800
Updated: 2021/12/16

DC Chemicals

Product number: DC21625
Product name: SBI-477
Purity: >98%
Packaging: 250mg
Price: $1600
Updated: 2021/12/16

DC Chemicals

Product number: DC21625
Product name: SBI-477
Purity: >98%
Packaging: 1g
Price: $3200
Updated: 2021/12/16

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Benzamide, 3-methoxy-N-[4-(4-methoxyphenyl)-2-thiazolyl]-4-[2-(4-morpholinyl)-2-oxoethoxy]- Chemical Properties,Usage,Production

Uses

SBI-477 is a chemical probe stimulated insulin signaling by deactivating the transcription factor MondoA, leading to reduced expression of the insulin pathway suppressors thioredoxin-interacting protein (TXNIP) and arrestin domain–containing 4 (ARRDC4). SBI-477 coordinately inhibits triacylglyceride (TAG) synthesis and enhances basal glucose uptake in human skeletal myocytes[1].

References

[1] Ahn B, et al. MondoA coordinately regulates skeletal myocyte lipid homeostasis and insulin signaling. J Clin Invest. 2016 Sep 1;126(9):3567-79. DOI:10.1172/JCI87382

Benzamide, 3-methoxy-N-[4-(4-methoxyphenyl)-2-thiazolyl]-4-[2-(4-morpholinyl)-2-oxoethoxy]- Preparation Products And Raw materials

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Benzamide, 3-methoxy-N-[4-(4-methoxyphenyl)-2-thiazolyl]-4-[2-(4-morpholinyl)-2-oxoethoxy]- Suppliers

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781628-99-7, Benzamide, 3-methoxy-N-[4-(4-methoxyphenyl)-2-thiazolyl]-4-[2-(4-morpholinyl)-2-oxoethoxy]-Related Search:

Benzamide, 3-methoxy-N-[4-(4-methoxyphenyl)-2-thiazolyl]-4-[2-(4-morpholinyl)-2-oxoethoxy]-

Inhibitor,SBI-477,inhibit,SBI 477,SBI477

3-Methoxy-N-(4-(4-methoxyphenyl)thiazol-2-yl)-4-(2-morpholino-2-oxoethoxy)benzamide

SBI-477, 10 mM in DMSO

781628-99-7