1-(BETA-D-Xylofuranosyl)-5-methylcytosine

Product Name: 1-(BETA-D-Xylofuranosyl)-5-methylcytosine
CAS No.: 18492-10-9
Chemical Name: 1-(BETA-D-Xylofuranosyl)-5-methylcytosine
Synonyms: 5-Methyl-xylo-cytidine;1-(b-D-Xylofuranosyl)-5-methylcytosine;1-(BETA-D-Xylofuranosyl)-5-methylcytosine;2(1H)-Pyrimidinone, 4-amino-5-methyl-1-β-D-xylofuranosyl-;4-amino-1-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidin-2(1H)-one
CBNumber: CB75493093
Molecular Formula: C10H15N3O5
Formula Weight: 257.2432
MOL File: 18492-10-9.mol

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1-(BETA-D-Xylofuranosyl)-5-methylcytosine Property

Melting point:: 205-207 °C(Solv: ethanol (64-17-5))
Boiling point:: 537.5±60.0 °C(Predicted)
Density: 1.79±0.1 g/cm3(Predicted)
pka: 13.48±0.70(Predicted)

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Hazard and Precautionary Statements (GHS)

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1-(BETA-D-Xylofuranosyl)-5-methylcytosine Chemical Properties,Usage,Production

Uses

1-(β-D-Xylofuranosyl)-5-methylcytosine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
[2] Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8. DOI:10.4161/cbt.3.11.1308

1-(BETA-D-Xylofuranosyl)-5-methylcytosine Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(BETA-D-Xylofuranosyl)-5-methylcytosine Suppliers

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18492-10-9, 1-(BETA-D-Xylofuranosyl)-5-methylcytosineRelated Search:

1-(BETA-D-Xylofuranosyl)-5-methylcytosine

5-Methyl-xylo-cytidine

1-(b-D-Xylofuranosyl)-5-methylcytosine

2(1H)-Pyrimidinone, 4-amino-5-methyl-1-β-D-xylofuranosyl-

4-amino-1-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidin-2(1H)-one

18492-10-9