ChemicalBook > CAS DataBase List > Ilorasertib hydrochloride
Ilorasertib hydrochloride
- Product Name
- Ilorasertib hydrochloride
- CAS No.
- 1847485-91-9
- Chemical Name
- Ilorasertib hydrochloride
- Synonyms
- ABT-348 hydrochloride;Ilorasertib hydrochloride;ILORASERTIB HYDROCHLORIDE (ABT-348 HYDROCHLORIDE)
- CBNumber
- CB75540379
- Molecular Formula
- C25H22ClFN6O2S
- Formula Weight
- 525
- MOL File
- 1847485-91-9.mol
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Ilorasertib hydrochloride Property
- storage temp.
- Store at -20°C
- solubility
- DMSO: 41.67 mg/mL (79.37 mM)
- form
- Solid
- color
- White to off-white
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0100459
- Product name
- Ilorasertib(hydrochloride)
- Purity
- 98.91%
- Packaging
- 1mg
- Price
- $70
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0100459
- Product name
- Ilorasertib(hydrochloride)
- Purity
- 98.91%
- Packaging
- 5mg
- Price
- $110
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0100459
- Product name
- Ilorasertib(hydrochloride)
- Purity
- 98.91%
- Packaging
- 10mg
- Price
- $150
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0100459
- Product name
- Ilorasertib(hydrochloride)
- Purity
- 98.91%
- Packaging
- 50mg
- Price
- $600
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0100459
- Product name
- Ilorasertib(hydrochloride)
- Purity
- 98.91%
- Packaging
- 100mg
- Price
- $1100
- Updated
- 2021/12/16
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Ilorasertib hydrochloride Chemical Properties,Usage,Production
Description
Ilorasertib hydrochloride (ABT-348 hydrochloride) is a potent and ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora B, and Aurora A with IC50s of 1 nM, 7 nM, 120 nM, respectively. Ilorasertib hydrochloride (ABT-348 hydrochloride) also suppresses RET tyrosine kinase, PDGFRβ and Flt1 with IC50s of 7 nM, 3 nM and 32 nM, respectively[1].
References
[1]. Glaser KB, et al. Preclinical characterization of ABT-348, a kinase inhibitor targeting the aurora, vascular endothelial growth factor receptor/platelet-derived growth factor receptor, and Src kinase families. J Pharmacol Exp Ther. 2012 Dec;343(3):617-27.
Ilorasertib hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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