Fz7-21

Product Name: Fz7-21
CAS No.: 2247635-23-8
Chemical Name: Fz7-21
Synonyms: Fz7-21;(Ac)-LPSDDLEFWCHVMY-NH2;Ac-Leu-Pro-Ser-Asp-Asp-Leu-Glu-Phe-Trp-Cys-His-Val-Met-Tyr-NH2;lipid-binding groove,FZD7,Wnt,Fz7 21,Wnt–β-catenin,Fz-7-21,conformation,FZD7 CRD,intestinal organoids,Fz7-21,Inhibitor,Fz721,inhibit
CBNumber: CB75590031
Molecular Formula: C83H114N18O23S2
Formula Weight: 1796.05
MOL File: 2247635-23-8.mol

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Fz7-21 Property

Boiling point:: 2088.7±65.0 °C(Predicted)
Density: 1.358±0.06 g/cm3(Predicted)
pka: 4.15±0.10(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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Fz7-21 Chemical Properties,Usage,Production

Uses

Fz7-21 (Ac-LPSDDLEFWCHVMY-NH2) is a potent peptide antagonist of FZD7 receptors , selectively binds to FZD7 CRD subclass and alters the conformation of the CRD and the architecture of its lipid-binding groove. The EC50 values are 58 and 34 nM for human and mouse FZD7 CRD, respectively. Fz7-21 impairs the function of FZD7 in Wnt–β-catenin signalling and stem cell function in intestinal organoids[1][2].

storage

-20°C

References

[1] Nile AH, et, al. A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells. Nat Chem Biol. 2018 Jun;14(6):582-590. DOI:10.1038/s41589-018-0035-2
[2] Larasati Y, et, al. Unlocking the Wnt pathway: Therapeutic potential of selective targeting FZD7 in cancer. Drug Discov Today. 2022 Mar;27(3):777-792. DOI:10.1016/j.drudis.2021.12.008

Fz7-21 Preparation Products And Raw materials

Raw materials

Preparation Products

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Fz7-21 Suppliers

China 28 United States 3 Global 31

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

Creative Peptides

Tel
Email: info@creative-peptides.com
Country: United States
ProdList: 6083
Advantage: 56

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 18101056239
Email: 3193328036@qq.com
Country: China
ProdList: 29661
Advantage: 68

Chengdu Youngshe Chemical Co., Ltd.

Tel: +86-17380623303 +86-17380623303;
Fax: 028-62328193
Email: Caroline@youngshechem.com
Country: China
ProdList: 4801
Advantage: 58

Hangzhou Peptidego Biotech Co.,Ltd.

Tel: 0571-87213919
Email: Eric@peptidego.com
Country: China
ProdList: 7618
Advantage: 58

Shanghai Han-Xiang Chemical Co., Ltd.

Tel: 15971444841
Fax: 18327183813
Email: amber@biochempartner.com
Country: China
ProdList: 3061
Advantage: 58

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19552
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career henan chemical co

Tel: +86-0371-86658258 +8613203830695
Fax: 0086-371-86658258
Email: factory@coreychem.com
Country: China
ProdList: 29794
Advantage: 58

Wuxi Helen Biotechnology Co., Ltd.,

Tel: 0510-85629785 18013409632
Fax: 0510-85625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 14081
Advantage: 58

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View Lastest Price from Fz7-21 manufacturers

Career Henan Chemical Co

Product: Fz7-21 2247635-23-8
Price: US $1.00/g
Min. Order: 1g
Purity: ≥98%
Supply Ability: g/kg/Ton
Release date: 2020-03-05

2247635-23-8, Fz7-21Related Search:

Fz7-21

Ac-Leu-Pro-Ser-Asp-Asp-Leu-Glu-Phe-Trp-Cys-His-Val-Met-Tyr-NH2

(Ac)-LPSDDLEFWCHVMY-NH2

lipid-binding groove,FZD7,Wnt,Fz7 21,Wnt–β-catenin,Fz-7-21,conformation,FZD7 CRD,intestinal organoids,Fz7-21,Inhibitor,Fz721,inhibit

2247635-23-8

C83H114N18O23S2