STAT5-IN-2
- Product Name
- STAT5-IN-2
- CAS No.
- 2111834-61-6
- Chemical Name
- STAT5-IN-2
- Synonyms
- STAT5-IN-2;STAT5-IN-2 ，E2398;STAT5 inhibitor 17f;STAT5-IN-2, 10 mM in DMSO;STAT-5-IN-2,STAT5IN2,STAT5 IN 2;1-(2-((1H-Indol-5-yl)oxy)ethyl)-4,4-dimethyl-6-(pyridin-3-yl)-1,2,3,4-tetrahydroquinoline;Quinoline, 1,2,3,4-tetrahydro-1-[2-(1H-indol-5-yloxy)ethyl]-4,4-dimethyl-6-(3-pyridinyl)-
- CBNumber
- CB75821403
- Molecular Formula
- C26H27N3O
- Formula Weight
- 397.51
- MOL File
- 2111834-61-6.mol
STAT5-IN-2 Property
- Boiling point:
- 635.5±55.0 °C(Predicted)
- Density
- 1.160±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO : 100 mg/mL (251.57 mM; Need ultrasonic)
- pka
- 16.56±0.30(Predicted)
- form
- Solid
- color
- Off-white to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- CS-0022841
- Product name
- STAT5-IN-2
- Purity
- 99.01%
- Packaging
- 5mg
- Price
- $400
- Updated
- 2021/12/16
- Product number
- CS-0022841
- Product name
- STAT5-IN-2
- Purity
- 99.01%
- Packaging
- 10mg
- Price
- $680
- Updated
- 2021/12/16
- Product number
- CS-0022841
- Product name
- STAT5-IN-2
- Purity
- 99.01%
- Packaging
- 50mg
- Price
- $1950
- Updated
- 2021/12/16
- Product number
- CS-0022841
- Product name
- STAT5-IN-2
- Purity
- 99.01%
- Packaging
- 100mg
- Price
- $2800
- Updated
- 2021/12/16
STAT5-IN-2 Chemical Properties,Usage,Production
Uses
STAT5-IN-2 is a STAT5 inhibitor, extracted from reference 1, example 17f. STAT5-IN-2 has potent antileukemic effect[1].
IC 50
STAT5: 9 μM (EC50, in K562 cells); STAT5: 5 μM (EC50, in KU812 cells )
References
[1] Ludovic Juen, et al. New Inhibitor Targeting Signal Transducer and Activator of Transcription 5 (STAT5) Signaling in Myeloid Leukemias. J Med Chem. 2017 Jul 27;60(14):6119-6136. DOI:10.1021/acs.jmedchem.7b00369
STAT5-IN-2 Preparation Products And Raw materials
Raw materials
Preparation Products
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