TAT-GluA2 3Y

Product Name: TAT-GluA2 3Y
CAS No.: 1404188-93-7
Chemical Name: TAT-GluA2 3Y
Synonyms: TAT-GluA2 3Y;TAT-GluA2 3Y TFA;Glycine, L-tyrosylglycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginyl-L-tyrosyl-L-lysyl-L-α-glutamylglycyl-L-tyrosyl-L-asparaginyl-L-valyl-L-tyrosyl-
CBNumber: CB75849324
Molecular Formula: C115H185N43O29
Formula Weight: 2634.02
MOL File: 1404188-93-7.mol

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TAT-GluA2 3Y Property

Density: 1.52±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 6847
Product name: TAT-GluA23Y
Packaging: 1
Price: $159
Updated: 2021/12/16

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TAT-GluA2 3Y Chemical Properties,Usage,Production

Uses

TAT-GluA2 3Y, an interference peptide, blocks long-term depression (LTD) at glutamatergic synapses by disrupting the endocytosis of AMPAR. TAT-GluA2 3Y can alleviate Pentobarbital-induced spatial memory deficits and synaptic depression[1][2][3].

References

[1] Choi FY, et, al. Interference with AMPA receptor endocytosis: effects on behavioural and neurochemical correlates of amphetamine sensitization in male rats. J Psychiatry Neurosci. 2014 May;39(3):189-99. DOI:10.1503/jpn.120257
[2] Chen Z, et, al. Prolonged adenosine A1 receptor activation in hypoxia and pial vessel disruption focal cortical ischemia facilitates clathrin-mediated AMPA receptor endocytosis and long-lasting synaptic inhibition in rat hippocampal CA3-CA1 synapses: differential regulation of GluA2 and GluA1 subunits by p38 MAPK and JNK. J Neurosci. 2014 Jul 16;34(29):9621-43. DOI:10.1523/JNEUROSCI.3991-13.2014

TAT-GluA2 3Y Preparation Products And Raw materials

Raw materials

Preparation Products

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TAT-GluA2 3Y Suppliers

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TAT-GluA2 3Y

Glycine, L-tyrosylglycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginyl-L-tyrosyl-L-lysyl-L-α-glutamylglycyl-L-tyrosyl-L-asparaginyl-L-valyl-L-tyrosyl-

TAT-GluA2 3Y TFA

1404188-93-7

C115H185N43O29