BEZAFIBRATE-D4

Product Name: BEZAFIBRATE-D4
CAS No.: 1189452-53-6
Chemical Name: BEZAFIBRATE-D4
Synonyms: BEZAFIBRATE-D4;[2H4]-Bezafibrate;2-{4-[2-(4-Chlorobenzamido-d4)ethyl]phenozy}-2-methylpropanoic Acid;Bezafibrate d4Q: What is Bezafibrate d4 Q: What is the CAS Number of Bezafibrate d4 Q: What is the storage condition of Bezafibrate d4 Q: What are the applications of Bezafibrate d4
CBNumber: CB7648344
Molecular Formula: C19H20ClNO4
Formula Weight: 361.8194
MOL File: 1189452-53-6.mol

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BEZAFIBRATE-D4 Property

Melting point:: 181-184°C
storage temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility: Acetone, DMSO (Slightly), Methanol
form: Solid
color: White to Off-White
Stability:: Hygroscopic

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 28526
Product name: Bezafibrate-d4
Packaging: 1mg
Price: $299
Updated: 2024/03/01

TRC

Product number: B341002
Product name: Bezafibrate-d4
Packaging: 10mg
Price: $1210
Updated: 2021/12/16

AK Scientific

Product number: 5486DF
Product name: Bezafibrate-d4
Packaging: 1mg
Price: $430
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: RDL0014312
Product name: BEZAFIBRATE-D4
Purity: 95.00%
Packaging: 5MG
Price: $498.96
Updated: 2021/12/16

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BEZAFIBRATE-D4 Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

Bezafibrate-d4 is deuterium labeled Bezafibrate. Bezafibrate is an agonist of PPAR, with EC50s of 50 μM, 60 μM, 20 μM for human PPARα, PPARγ and PPARδ, and 90 μM, 55 μM, 110 μM for murine PPARα, PPARγ and PPARδ, respectively; Bezafibrate is used as an hypolipidemic agent.

References

[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
[2] Willson TM, et al. The PPARs: from orphan receptors to drug discovery. J Med Chem. 2000 Feb 24;43(4):527-50. DOI:10.1021/jm990554g
[3] Usui-Ouchi A, et al. The peroxisome proliferator-activated receptor pan-agonist bezafibrate suppresses microvascular inflammatory responses of retinal endothelial cells and vascular endothelial growth factor production in retinal pigmented epithelial cells. Int Immunopharmacol. 2017 Nov;52:70-76. DOI:10.1016/j.intimp.2017.08.027
[4] Franko A, et al. Bezafibrate ameliorates diabetes via reduced steatosis and improved hepatic insulin sensitivity in diabetic TallyHo mice. Mol Metab. 2017 Jan 6;6(3):256-266. DOI:10.1016/j.molmet.2016.12.007

BEZAFIBRATE-D4 Preparation Products And Raw materials

Raw materials

Preparation Products

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BEZAFIBRATE-D4 Suppliers

Canada 1 China 23 India 4 United States 2 Global 30

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Cato Research Chemicals Inc.

Tel: 020-81960175
Fax: +1-541-2553641
Email: min.he@cato-chem.com
Country: China
ProdList: 1955
Advantage: 55

Nanjing Haolv Biotechnology Co.,Ltd

Tel: 025-84622273 17361806303
Email: kexin.zhou@haolvbiotech.com
Country: China
ProdList: 3019
Advantage: 58

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6777
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57422
Advantage: 58

Hangzhou Huarong Pharm Co., Ltd.

Tel: 571-86758373 +8613588754946
Fax: 0086-571-81131109
Email: sales@huarongpharm.com
Country: CHINA
ProdList: 3148
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44894
Advantage: 58

TCI (Shanghai) Chemical Trading Co., Ltd.

Tel: 021-61109150
Fax: 021-61105897
Email: sales@tcisct.com
Country: China
ProdList: 29668
Advantage: 58

Shanghai isotope chemical co.,ltd

Tel: 021-51600108 13062666369
Email: sales@isotopechem.com
Country: China
ProdList: 5000
Advantage: 58

1189452-53-6, BEZAFIBRATE-D4Related Search:

Bezafibrate Impurity 6 Benzamide, 3-chloro-N-[2-(4-hydroxyphenyl)ethyl]- Bezafibrate Acyl Glucuronide Bezafibrate Impurity D Bezafibrate Impurity 5 Bezafibrate Impurity 8 Propanoic acid, 2-[4-(2-aminoethyl)phenoxy]-2-methyl- Bezafibrate EP Impurity E Bezafibrate Impurity 4 Bezafibrate EP Impurity C [4-[2-[(4-chlorobenzoyl)amino]ethyl]phenyl] 4-chlorobenzoate Bezafibrate Impurity 7 Benzamide, 2-chloro-N-[2-(4-hydroxyphenyl)ethyl]- N-(4-Chlorobenzoyl)-tyramine Bezafibrate

BEZAFIBRATE-D4

2-{4-[2-(4-Chlorobenzamido-d4)ethyl]phenozy}-2-methylpropanoic Acid

[2H4]-Bezafibrate

Bezafibrate d4Q: What is Bezafibrate d4 Q: What is the CAS Number of Bezafibrate d4 Q: What is the storage condition of Bezafibrate d4 Q: What are the applications of Bezafibrate d4

1189452-53-6

C19H16D4ClNO4

Isotope Labeled Compounds

Isotope Labelled Compounds