BOC-IMINODIACETIC ACID
- Product Name
- BOC-IMINODIACETIC ACID
- CAS No.
- 56074-20-5
- Chemical Name
- BOC-IMINODIACETIC ACID
- Synonyms
- BOC-IDA;BOC-IDA-OH;Boc-DL-Ida-OH;Glycine impurity 1;RARECHEM EM WB 0140;BOC-IMINODIACETIC ACI;BOC-IMINODIACETIC ACID;N-BOC-IMINODIACETIC ACID;(Tert-Butoxy)Carbonyl Ida-OH;N-Boc-Iminodiacetic Acid, ≥98%
- CBNumber
- CB7711729
- Molecular Formula
- C9H15NO6
- Formula Weight
- 233.22
- MOL File
- 56074-20-5.mol
BOC-IMINODIACETIC ACID Property
- Melting point:
- 117-120 °C
- Boiling point:
- 412.0±38.0 °C(Predicted)
- Density
- 1.316±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Methanol
- form
- Powder
- pka
- 3.45±0.10(Predicted)
- color
- White
- BRN
- 4435233
Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29241990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 47997
- Product name
- N-Boc-iminodiacetic acid
- Purity
- ≥96.0% (HPLC)
- Packaging
- 5g
- Price
- $170
- Updated
- 2023/01/07
- Product number
- B4368
- Product name
- N-(tert-Butoxycarbonyl)iminodiacetic Acid
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $33
- Updated
- 2025/07/31
- Product number
- B4368
- Product name
- N-(tert-Butoxycarbonyl)iminodiacetic Acid
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 25g
- Price
- $112
- Updated
- 2025/07/31
- Product number
- B648463
- Product name
- Boc-IminodiaceticAcid
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 264973
- Product name
- Boc-iminodiacetic acid
- Packaging
- 25g
- Price
- $389
- Updated
- 2021/12/16
BOC-IMINODIACETIC ACID Chemical Properties,Usage,Production
Chemical Properties
White crystalline
Uses
Building block for preparing chemical libraries
Uses
Boc-Iminodiacetic Acid can be used as a novel α4β7 integrin peptide antagonists.
Synthesis
24424-99-5
142-73-4
56074-20-5
General procedure: A mixture of iminodiacetic acid (5.1 g, 38.3 mmol) and sodium bicarbonate (NaHCO3, 12.9 g, 153 mmol) was dissolved in 50 mL of water. After the gas release stopped, 50 mL of tetrahydrofuran (THF) was added, followed by the slow addition of di-tert-butyl dicarbonate (Boc2O, 10.0 g, 46.0 mmol). The reaction mixture was stirred at room temperature for 2 days and the progress of the reaction was monitored by electrospray ionization mass spectrometry (ESI-MS) until complete consumption of the feedstock. Upon completion of the reaction, THF was removed by rotary evaporation and the aqueous phase was washed twice with ether (Et2O). Subsequently, the pH of the aqueous phase was adjusted with concentrated hydrochloric acid to 1. The product was extracted with ethyl acetate (EtOAc), and after combining the organic phases, the solvent was removed by rotary evaporation to give a white solid product. The product was further purified by recrystallization from ethyl acetate to give N-Boc-iminodiacetic acid (8.04 g, 90% yield) as clear crystals.ESI-MS detection showed [M-H]- peak at m/z 232.1.
References
[1] Journal of Medicinal Chemistry, 1996, vol. 39, # 8, p. 1601 - 1608
[2] Patent: WO2004/35576, 2004, A2. Location in patent: Page 170
[3] Patent: WO2005/117904, 2005, A2. Location in patent: Page/Page column 404-405
[4] Tetrahedron, 1996, vol. 52, # 29, p. 9793 - 9804
[5] Bioorganic and Medicinal Chemistry, 1998, vol. 6, # 8, p. 1347 - 1378
BOC-IMINODIACETIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from BOC-IMINODIACETIC ACID manufacturers
- Product
- BOC-IMINODIACETIC ACID 56074-20-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20kg
- Release date
- 2018-08-15
- Product
- BOC-IMINODIACETIC ACID 56074-20-5
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000KG
- Release date
- 2018-08-15