ChemicalBook > CAS DataBase List > ETHYL 3,4-DIHYDROXYCINNAMATE

ETHYL 3,4-DIHYDROXYCINNAMATE

Product Name
ETHYL 3,4-DIHYDROXYCINNAMATE
CAS No.
66648-50-8
Chemical Name
ETHYL 3,4-DIHYDROXYCINNAMATE
Synonyms
Zinc01614326;ethyl (E)-caffeate;Ethyl trans-caffeate;E-Caffeic acid ethyl ester;Ethyl-3,4-dihydroxycinnamte;(E)-Ethyl Dihydroxycinnamate;ETHYL 3,4-DIHYDROXYCINNAMATE;Ethyl 3,4-dihydroxycinnamate,97%;Ethyl transcaffeate,Ethyl trans caffeate;2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-, ethyl ester, (2E)-
CBNumber
CB7713697
Molecular Formula
C11H12O4
Formula Weight
208.21
MOL File
66648-50-8.mol
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ETHYL 3,4-DIHYDROXYCINNAMATE Property

Melting point:
147~151℃
Boiling point:
148-149 °C
Density 
1.271±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
8.71±0.18(Predicted)
form 
Off-white to brown solid.
LogP
2.418 (est)
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Safety

Hazard Codes 
Xn
Risk Statements 
36/37/38-22
Safety Statements 
26-36
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SMB01081
Product name
Ethyl 3,4-Dihydroxycinnamate
Purity
≥90% (LC/MS-ELSD)
Packaging
1MG
Price
$417
Updated
2024/03/01
Sigma-Aldrich
Product number
PHL83086
Product name
Ethyl trans-caffeate
Purity
phyproof? Reference Substance
Packaging
100mg
Price
$312
Updated
2024/03/01
Sigma-Aldrich
Product number
CDS000693
Product name
Ethyl 3,4-dihydroxycinnamate
Purity
AldrichCPR
Packaging
100mg
Price
$70.9
Updated
2024/03/01
Alfa Aesar
Product number
B24808
Product name
Ethyl 3,4-dihydroxycinnamate, 97%
Packaging
1g
Price
$45.4
Updated
2024/03/01
Alfa Aesar
Product number
B24808
Product name
Ethyl 3,4-dihydroxycinnamate, 97%
Packaging
5g
Price
$140
Updated
2024/03/01
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ETHYL 3,4-DIHYDROXYCINNAMATE Chemical Properties,Usage,Production

Uses

Ethyl 3,4-dihydroxycinnamate shows anti-inflammatory, immunomodulatory, and anti-carcinogenic properties. It is a potent and specific inhibitor of NF-κB and its downstream inflammatory mediators: NOS2 (inducible nitric oxide synthase; NOS; NOS II), Cox-2 (cyclooxygenase-2), and prostaglandin E2 (PGE2). Ethyl 3,4-Dihydroxycinnamate prevents DNA single-strand breaks caused by H2O2.

Definition

ChEBI: Ethyl trans-caffeate is an ethyl ester resulting from the formal condensation of the carboxy group of trans-caffeic acid with ethanol. It has a role as an anti-inflammatory agent and an antineoplastic agent. It is an alkyl caffeate ester and an ethyl ester. It is functionally related to a trans-caffeic acid.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

ETHYL 3,4-DIHYDROXYCINNAMATE Preparation Products And Raw materials

Raw materials

Preparation Products

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66648-50-8, ETHYL 3,4-DIHYDROXYCINNAMATERelated Search:


  • ETHYL 3,4-DIHYDROXYCINNAMATE
  • 2-Propenoicacid,3-(3,4-dihydroxyphenyl)-,ethylester,(2E)-(9CI)
  • E-Caffeic acid ethyl ester
  • Ethyl trans-caffeate
  • (E)-Ethyl Dihydroxycinnamate
  • Zinc01614326
  • Ethyl-3,4-dihydroxycinnamte
  • 2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-, ethyl ester, (2E)-
  • ethyl (E)-caffeate
  • Ethyl 3,4-dihydroxycinnamate,97%
  • Ethyl transcaffeate,Ethyl trans caffeate
  • 66648-50-8
  • ALCOHOL
  • Aromatic Esters