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METHYL-D3-MALONIC ACID

Product Name
METHYL-D3-MALONIC ACID
CAS No.
42522-59-8
Chemical Name
METHYL-D3-MALONIC ACID
Synonyms
NSC 2520-d3;Isosuccinic Acid-d3;MethylMalonic Acid-d3;METHYL-D3-MALONIC ACID;Methyl-d?-malonic acid;[2H3]-Methylmalonic Acid;Methyl-d3-propanedioic Acid;2-Methylpropanedioic acid D3;2-METHYL-D3-PROPANEDIOIC ACID;1,1-Ethanedicarboxylic Acid-d3
CBNumber
CB7715949
Molecular Formula
C4H3D3O4
Formula Weight
121.11
MOL File
42522-59-8.mol
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METHYL-D3-MALONIC ACID Property

Melting point:
134-136 °C(lit.)
Flash point:
2 °C
storage temp. 
-20°C
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Off-White
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Safety

Hazard Codes 
Xn,F
Risk Statements 
20/22-36/37/38-36-20/21/22-11
Safety Statements 
26-36-36/37-16
RIDADR 
UN 1648 3 / PGII
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M-105
Product name
Methyl-D3-malonic acid solution
Purity
1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?
Packaging
1mL
Price
$180
Updated
2024/03/01
Sigma-Aldrich
Product number
490318
Product name
Methyl-d3-malonic acid
Purity
98 atom % D
Packaging
250mg
Price
$820
Updated
2024/03/01
TRC
Product number
M318862
Product name
MethylmalonicAcid-d3
Packaging
10mg
Price
$120
Updated
2021/12/16
Usbiological
Product number
017011
Product name
Methylmalonic Acid-d3
Packaging
10mg
Price
$382
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
RDL0013270
Product name
METHYL-D3-MALONIC ACID
Purity
95.00%
Packaging
5MG
Price
$499.68
Updated
2021/12/16
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METHYL-D3-MALONIC ACID Chemical Properties,Usage,Production

Chemical Properties

White to Off-White Solid

Uses

An isotope labelled derivative of Methylmalonic Acid (M318860), binds with coenzyme A to form methylmalonyl-CoA, also a metabolic intermediate transformed to succinic acid (SA) by a vitamin B12-dependent catalytic step, and is broadly used as a clinical biomarker of functional vitamin B12 status.

Uses

Methyl-d3-malonic acid is an isotope labelled derivative of Methylmalonic Acid (M318860), binds with coenzyme A to form methylmalonyl-CoA, also a metabolic intermediate transformed to succinic acid (SA) by a vitamin B12-depend ent catalytic step, and is broadly used as a clinical biomarker of functional vitamin B12 status.

General Description

Methylmalonic acid, a malonic acid derivative, is a vital intermediate in the metabolism of fat and proteins and plays a key role in energy metabolism. Elevated methylmalonic acid levels can be caused by an inborn error of metabolism leading to methylmalonic aciduria or indicate early vitamin B<sub>12</sub> deficiency. This internal standard is suitable for quantitation of methylmalonic acid levels by LC/MS or GC/MS in newborn screening and clinical testing applications to test for methylmalonic acidemia and diagnose vitamin B<sub>12</sub> deficiency.

METHYL-D3-MALONIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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METHYL-D3-MALONIC ACID Suppliers

J & K SCIENTIFIC LTD.
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+91-22-26355701
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Shenzhen Polymeri Biochemical Technology Co., Ltd.
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42522-59-8, METHYL-D3-MALONIC ACIDRelated Search:


  • METHYL-D3-MALONIC ACID, 98 ATOM % D
  • METHYLMALONIC ACID (METHYL-D3)
  • METHYL-D3-MALONIC ACID
  • 2-METHYL-D3-PROPANEDIOIC ACID
  • 1,1-Ethanedicarboxylic Acid-d3
  • Isosuccinic Acid-d3
  • Methyl-d3-propanedioic Acid
  • NSC 2520-d3
  • Methyl-D3-malonic acid solution
  • MethylMalonic Acid-d3
  • 2-Methylpropanedioic acid D3
  • Methylmalonic Acid-[d3] (Solution)
  • [2H3]-Methylmalonic Acid
  • 2-(trideuteriomethyl)propanedioic acid
  • Methyl-d?-malonic acid
  • Methyl-d3-malonic acid in methanol
  • 42522-59-8
  • CD3CHCO2H2
  • C4H3D3O4
  • CD3CHCOOH2
  • Stable Isotopes
  • BioChemical
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  • Stable Isotopes
  • Aliphatics
  • Intermediates & Fine Chemicals
  • Isotope Labelled Compounds
  • Metabolites & Impurities
  • Pharmaceuticals