5(S),6(R),15(S)-TRIHETE METHYL ESTER Property

Boiling point:

540.2±50.0 °C(Predicted)

Density 

1.056±0.06 g/cm3(Predicted)

Flash point:

10℃ (tag closed test)

storage temp. 

Store at -80°C

solubility 

DMF: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 1 mg/ml

pka

13.38±0.20(Predicted)

Hazard and Precautionary Statements (GHS)

5(S),6(R),15(S)-TRIHETE METHYL ESTER Chemical Properties,Usage,Production

Description

Lipoxin A₄ methyl ester (LXA₄ methyl ester) is a more lipid soluble, prodrug formulation of the transcellular metabolite LXA₄. LXA₄ is a trihydroxy fatty acid containing a conjugated tetraene, produced by the metabolism of 15-HETE or 15-HpETE with human leukocytes. LXA₄ is equipotent to leukotriene B₄ (LTB₄) in inducing superoxide generation in human neutrophils at 0.1 μM. LXA₄ is associated with several other biological functions including leukocyte activation, chemotaxis effects, natural killer cell inhibition, and monocyte migration and adhesion.