GALNON
- Product Name
- GALNON
- CAS No.
- 475115-35-6
- Chemical Name
- GALNON
- Synonyms
- GALNON;FMoc-Cha-Lys-AMC;Galnon, Fmoc-Cha-Lys-AMC;FMoc-b-cyclohexyl-Ala-Lys-AMC;FMOC-BETA-CYCLOHEXYL-ALA-LYS-AMC;3-CYCLOHEXYL-N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-L-ALANYL-N-(4-METHYL-2-OXO-2H-1-BENZOPYRAN-7-YL)-L-LYSINAMIDE;L-Lysinamide, 3-cyclohexyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
- CBNumber
- CB7740387
- Molecular Formula
- C40H46N4O6
- Formula Weight
- 678.82
- MOL File
- 475115-35-6.mol
GALNON Property
- Boiling point:
- 937.5±65.0 °C(Predicted)
- Density
- 1.242±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- H2O: insoluble
- form
- solid
- pka
- 10.68±0.46(Predicted)
- color
- white
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- 2085
- Product name
- Galnon
- Packaging
- 10
- Price
- $139
- Updated
- 2021/12/16
- Product number
- 451063
- Product name
- Galnon
- Packaging
- 1mg
- Price
- $305
- Updated
- 2021/12/16
- Product number
- 255352
- Product name
- Galnon
- Packaging
- 10mg
- Price
- $389
- Updated
- 2021/12/16
- Product number
- B5256
- Product name
- Galnon
- Packaging
- 10mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- API0009345
- Product name
- GALNON
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $653.68
- Updated
- 2021/12/16
GALNON Chemical Properties,Usage,Production
Uses
Galnon is a selective and non-peptide agonist of galanin GAL1 and GAL2 receptor, with Kis of 11.7 and 34.1 μM respectively. Galnon exhibits anticonvulsant and anxiolytic effects[1][2].
Biological Activity
Novel non-peptide galanin GAL 1 receptor agonist (K i = 4.8 μ M). Stimulates insulin release in isolated pancreatic islets from normal and diabetic rats. Systemically active in vivo ; displays anticonvulsant activity following i.p. administration in mice. Central and peripheral administration also transiently inhibits food intake in rats and mice.
References
[1] Bartfai T, et, al. Galmic, a nonpeptide galanin receptor agonist, affects behaviors in seizure, pain, and forced-swim tests. Proc Natl Acad Sci U S A. 2004 Jul 13;101(28):10470-5. DOI:10.1073/pnas.0403802101
[2] Rajarao SJR, et, al. Anxiolytic-like activity of the non-selective galanin receptor agonist, galnon. Neuropeptides. 2007 Oct;41(5):307-20. DOI:10.1016/j.npep.2007.05.001
GALNON Preparation Products And Raw materials
Raw materials
Preparation Products
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