ChemicalBook > CAS DataBase List > Pizotifen Malate

Pizotifen Malate

Product Name: Pizotifen Malate
CAS No.: 5189-11-7
Chemical Name: Pizotifen Malate
Synonyms: mosegor;sanomtgran;bc105malate;litecmalate;malate(1:1);Pizotifen Mala;Einecs 225-970-4;PIZOTIFEN MALATE;sandomygranmalate;PIZOTYLINE MALATE
CBNumber: CB7754050
Molecular Formula: C23H27NO5S
Formula Weight: 429.53
MOL File: 5189-11-7.mol

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Pizotifen Malate Property

Melting point:: 185-186° (dec)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
solubility: Aqueous Acid (Slightly, Heated), DMSO (Slightly), Methanol (Slightly)
form: Solid
color: White to Off-White
Stability:: Hygroscopic

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-37/39

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: BP411
Product name: Pizotifen malate
Purity: British Pharmacopoeia (BP) Reference Standard
Packaging: 50 mg
Price: $313
Updated: 2025/07/31

Cayman Chemical

Product number: 20765
Product name: Pizotifen (malate)
Purity: ≥98%
Packaging: 100mg
Price: $28
Updated: 2024/03/01

Cayman Chemical

Product number: 20765
Product name: Pizotifen (malate)
Purity: ≥98%
Packaging: 250mg
Price: $60
Updated: 2024/03/01

Cayman Chemical

Product number: 20765
Product name: Pizotifen (malate)
Purity: ≥98%
Packaging: 500mg
Price: $78
Updated: 2024/03/01

Cayman Chemical

Product number: 20765
Product name: Pizotifen (malate)
Purity: ≥98%
Packaging: 1g
Price: $117
Updated: 2024/03/01

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Pizotifen Malate Chemical Properties,Usage,Production

Uses

Antimigraine

Uses

Pizotifen, C19H21NS· C4H6O5, is piperidine derivatives. Though antihistamines, it is mainly used because of their antiserotonergic properties.

Uses

Pizotifen Malate is an anti migraine drug.

Definition

ChEBI: A malate salt resulting from the reaction of equimolar amounts of pizotifen and malic acid. A sedating antihistamine with strong serotonin antagonist and weak antimuscarinic activity, it is used for the treatment of migraine and the prevention of headache ttacks during cluster periods.

in vivo

The weights of the fetuses are significantly reduced by all administered doses of Pipethiadene and Pizotifen malate (BC-105 malate) ; the weights of the placentas are significantly reduced after 0.6 and 1.2 mg/kg Pipethiadene and only after the middle dose of Pizotifen malate. The means of the implantations, live, dead fetuses, resorptions and the occurrence of external, skeletal and visceral anomalies do not differ from the control group. The number of chromosome aberrations in the bone marrow cells of treated mice does not differ significantly from the negative control group. The micronucleus test reveals no elevation in the frequency of micronuclei as compared to the control group. After the two higher doses of both Pipethiadene and Pizotifen maleate, the mitotic indices are lower than in the control group^[3].

IC 50

5-HT_2A Receptor; 5-HT_1C Receptor

Pizotifen Malate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Pizotifen Malate manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: Pizotifen Malate 5189-11-7
Price: US $0.10/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 1000 tons
Release date: 2025-09-11

Shandong Xuhuang New material CoLTD

Product: Pizotifen Malate 5189-11-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99.99%
Supply Ability: 200
Release date: 2025-02-21

Zhuozhou Wenxi import and Export Co., Ltd

Product: Pizotifen Malate 5189-11-7
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

5189-11-7, Pizotifen MalateRelated Search:

EC 1.1.1.40 (2R,6S)-rel-2,6-DiMethyl-4-(2-Methyl-3-phenylpropyl)Morpholine Hydrochloride Fenpropimorph 4-[3-[4-(1,1-diMethylpropyl)-phenyl]-2-Methylpropyl]-2,6-diMethylMorpholine 4-oxide N-[2-(acetyloxy)propyl]-N-[3-[4-(1,1-diMethylpropyl)phenyl]-2-Methylpropyl]-forMaMide Pizotifen Pizotifen Malate 3-BENZYLTHIOPHENE CYCLOHEPTANE 1-(2,6-Dichlorophenyl)-2-indolinone (METHOXYMETHYL)DIPHENYLPHOSPHINE OXIDE IBD 78

sandomygranmalate

sanomtgran

4-(9,10-DIHYDRO-1-THIA-BENZO[F]AZULEN-4-YLIDENE)-1-METHYL-PIPERIDINE, COMPOUND WITH 2-HYDROXY-SUCCINIC ACID

PIZOTYLINE MALATE

PIZOTIFEN MALATE

9,10-Dihydro-4-(1-methylpiperidin-4-ylidene)-4H-benzo[4,5]cyclohepta[1,2-b]thiophene malate (1:1)

malic acid, compound with 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidine (1:1)

Einecs 225-970-4

Piperidine, 4-(9,10-dihydro-4H-benzo(4,5)cyclohepta(1,2-B)thien-4-ylidene)-1-methyl-, malate (1:1)

Malic acid, coMpound with 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-Methylpiperidine

Pizotifen Mala

bc105malate

litecmalate

malate(1:1)

mosegor

pizotifenhydrogenmalate

sandomigranmalate

Benzene thiamethoxam organism malate

Butanedioicacid, 2-hydroxy-, coMpd. with 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-Methylpiperidine(1:1)

4-(9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidinium hydrogen malate

9,10-Dihydro-4-(1-methylpiperidin-4-ylidene)-4H-benzo[4,5]cyclohepta[1,2-b]thiophene malate

Pizotifen Malate USP/EP/BP

malic acid, compound with 4-(9,10-dihydro-4H-benzo[4,5]cyclo...

4-(9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)-1-methylpiperidine 2-hydroxysuccinate

Litecmalate Powder USP Standard

Pizotifen Malate, 10 mM in DMSO

Pizotifen malate/BC-105 malate

5189-11-7

C23H27NO5S

C19H21NSC4H6O5

C19H21NSxC4H6O5

Active Pharmaceutical Ingredients

Sandomigran, pizotyline

API