ChemicalBook > CAS DataBase List > IFLAB-BB F1950-0211
IFLAB-BB F1950-0211
- Product Name
- IFLAB-BB F1950-0211
- CAS No.
- 1198098-03-1
- Chemical Name
- IFLAB-BB F1950-0211
- Synonyms
- WAY-119064;WAY-119064 ，E0798;IFLAB-BB F1950-0211;GSK-3β inhibitor 10;GSK-3β inhibitor 10, 10 mM in DMSO;(Z)-2-Amino-5-(3,4-dimethoxybenzylidene)thiazol-4(5H)-one;(5Z)-2-Amino-5-(3,4-dimethoxybenzylidene)-1,3-thiazol-4(5H)-one;(5Z)-5-(3,4-dimethoxybenzylidene)-2-imino-1,3-thiazolidin-4-one;4(5H)-Thiazolone, 2-amino-5-[(3,4-dimethoxyphenyl)methylene]-, (5Z)-;Inhibitor,Alzheimer’s disease,GSK-3,Glycogen synthase kinase-3,inhibit,Glycogen synthase kinase 3,WAY119064,GSK-3β inhibitor 10,WAY 119064
- CBNumber
- CB7755921
- Molecular Formula
- C12H12N2O3S
- Formula Weight
- 264.3
- MOL File
- Mol file
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IFLAB-BB F1950-0211 Property
- Boiling point:
- 454.8±55.0 °C(Predicted)
- Density
- 1.36±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: 13 mg/mL (49.19 mM);Ethanol: Insoluble
- pka
- -0.59±0.20(Predicted)
- form
- Solid
- color
- Light yellow to yellow
- Water Solubility
- Water: Insoluble
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IFLAB-BB F1950-0211 Chemical Properties,Usage,Production
Uses
GSK-3β inhibitor 10 (compound 14a) is a highly potent GSK-3β inhibitor with an IC50 value of 80.5 nM. GSK-3β inhibitor 10 can be used for researching Alzheimer’s disease[1].
Biological Activity
WAY-119064 is a potent glycogen synthase kinase-3β (GSK-3β) inhibitor with an IC50 value of 80.5 nM.
IC 50
GSK-3β: 80.5 nM (IC50)
References
[1] Arfeen M, et al. Eur J Med Chem. 2016 Oct 4;121:727-736.
IFLAB-BB F1950-0211 Preparation Products And Raw materials
Raw materials
Preparation Products
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