(+/-)-18-HYDROXY-5Z,8Z,11Z,14Z,16E-EICOSAPENTAENOIC ACID

Product Name: (+/-)-18-HYDROXY-5Z,8Z,11Z,14Z,16E-EICOSAPENTAENOIC ACID
CAS No.: 141110-17-0
Chemical Name: (+/-)-18-HYDROXY-5Z,8Z,11Z,14Z,16E-EICOSAPENTAENOIC ACID
Synonyms: (+/-)18-HEPE;LRWYBGFSVUBWMO-UXNZXXPISA-N;Eicosapentaenoic Acid Impurity 11;(+/-)-18-HYDROXY-5Z,8Z,11Z,14Z,16E-EICOSAPENTAENOIC ACID;(+/-)-18-HYDROXY-5Z,8Z,11Z,14Z,16E-EICOSAPENTAENOIC ACID;(5Z,8Z,11Z,14Z,16E)-18-Hydroxyicosa-5,8,11,14,16-pentaenoic acid;5,8,11,14,16-Eicosapentaenoic acid, 18-hydroxy-, (5Z,8Z,11Z,14Z,16E)-
CBNumber: CB7759853
Molecular Formula: C20H30O3
Formula Weight: 318.45
MOL File: 141110-17-0.mol

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(+/-)-18-HYDROXY-5Z,8Z,11Z,14Z,16E-EICOSAPENTAENOIC ACID Property

Boiling point:: 488.0±45.0 °C(Predicted)
Density: 0.997±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: 0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS (pH 7.2): 0.8 mg/ml
pka: 4.75±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 32840
Product name: (±)18-HEPE
Purity: ≥97%
Packaging: 25μg
Price: $117
Updated: 2024/03/01

Cayman Chemical

Product number: 32840
Product name: (±)18-HEPE
Purity: ≥97%
Packaging: 50μg
Price: $222
Updated: 2024/03/01

Cayman Chemical

Product number: 32840
Product name: (±)18-HEPE
Purity: ≥97%
Packaging: 100μg
Price: $418
Updated: 2024/03/01

Cayman Chemical

Product number: 32840
Product name: (±)18-HEPE
Purity: ≥97%
Packaging: 250μg
Price: $923
Updated: 2024/03/01

Cayman Chemical

Product number: 23567
Product name: (±)18-HEPE MaxSpec® Standard
Packaging: 10μg
Price: $151
Updated: 2022/04/27

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(+/-)-18-HYDROXY-5Z,8Z,11Z,14Z,16E-EICOSAPENTAENOIC ACID Chemical Properties,Usage,Production

Description

(±)18-HEPE is produced by non-enzymatic oxidation of eicosapentaenoic acid (EPA; Item Nos. 90110 | 90110.1 | 21908). 18-HEPE levels are increased in the plasma and heart, as well as in the supernatant of cultured peritoneal macrophages isolated from fat-1 transgenic mice that are capable of endogenously producing ω-3 fatty acids from ω-6 fatty acids. It reduces increases in cardiac fibrosis and the expression of Nppa, Col1a1, Tgfb1, Cx3cl1, and Adgre1 induced by transverse aortic constriction in a mouse model of cardiac hypertrophy when administered at doses of 1 and 5 μg.

Uses

18-Hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoic Acid is produced by non-enzymatic oxidation of Eicosapentaenoic Acid (E477800).

Definition

ChEBI: 18-HEPE is a hydroxyicosapentaenoic acid that consists of 5Z,8Z,11Z,14Z,16E-icosapentaenoic acid with the hydroxy group located at position 18. It has a role as a human xenobiotic metabolite. It is a conjugate acid of a 18-HEPE(1-).

(+/-)-18-HYDROXY-5Z,8Z,11Z,14Z,16E-EICOSAPENTAENOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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(+/-)-18-HYDROXY-5Z,8Z,11Z,14Z,16E-EICOSAPENTAENOIC ACID Suppliers

China 11 India 1 Switzerland 1 United States 6 Global 19

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141110-17-0, (+/-)-18-HYDROXY-5Z,8Z,11Z,14Z,16E-EICOSAPENTAENOIC ACIDRelated Search:

(+/-)-18-HYDROXY-5Z,8Z,11Z,14Z,16E-EICOSAPENTAENOIC ACID

(+/-)18-HEPE

LRWYBGFSVUBWMO-UXNZXXPISA-N

(5Z,8Z,11Z,14Z,16E)-18-Hydroxyicosa-5,8,11,14,16-pentaenoic acid

5,8,11,14,16-Eicosapentaenoic acid, 18-hydroxy-, (5Z,8Z,11Z,14Z,16E)-

Eicosapentaenoic Acid Impurity 11

(+/-)-18-HYDROXY-5Z,8Z,11Z,14Z,16E-EICOSAPENTAENOIC ACID

141110-17-0