ChemicalBook > CAS DataBase List > ECHINACOSIDE

ECHINACOSIDE

Product Name: ECHINACOSIDE
CAS No.: 82854-37-3
Chemical Name: ECHINACOSIDE
Synonyms: Cistanche tubulosa;Echicoside;Echinacoside, froM Cistanche deserticola Y.C.Ma;β-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl O-6-deoxy-α-L-mannopyranosyl-(1→3)-O-[β-D-glucopyranosyl-(1→6)]-, 4-[3-(3,4-dihydroxyphenyl)-2-propenoate];beta-d-e;Echinoside;ECHINACOSIDE;Echinacosidew; Purpureaside C;Echinacoside (P)
CBNumber: CB7772340
Molecular Formula: C35H46O20
Formula Weight: 786.73
MOL File: 82854-37-3.mol

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ECHINACOSIDE Property

Boiling point:: 1062.7±65.0 °C(Predicted)
Density: 1.66±0.1 g/cm3(Predicted)
storage temp.: Inert atmosphere,2-8°C
solubility: DMSO:60.0(Max Conc. mg/mL);76.26(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:9):0.1(Max Conc. mg/mL);0.13(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);38.13(Max Conc. mM)
Ethanol:52.5(Max Conc. mg/mL);66.73(Max Conc. mM)
Water:24.36(Max Conc. mg/mL);30.96(Max Conc. mM)
form: powder
pka: 8.43±0.20(Predicted)
color: White-beige
BRN: 4778612
Stability:: Hygroscopic
InChIKey: FSBUXLDOLNLABB-ISAKITKMSA-N
LogP: 0.140 (est)

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Safety

Safety Statements: 24/25
WGK Germany: 3
RTECS: LZ5786500
HS Code: 29389090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHL89188
Product name: Echinacoside
Purity: phyproof? Reference Substance
Packaging: 10MG
Price: $341
Updated: 2025/07/31

Sigma-Aldrich

Product number: 07538
Product name: Echinacoside
Purity: analytical standard
Packaging: 10mg
Price: $169
Updated: 2025/07/31

Sigma-Aldrich

Product number: 01710580
Product name: Echinacoside
Purity: primary pharmaceutical reference standard
Packaging: 10mg
Price: $389
Updated: 2023/06/20

Cayman Chemical

Product number: 29927
Product name: Echinacoside
Packaging: 5mg
Price: $62
Updated: 2024/03/01

Cayman Chemical

Product number: 29927
Product name: Echinacoside
Packaging: 10mg
Price: $109
Updated: 2024/03/01

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ECHINACOSIDE Chemical Properties,Usage,Production

Description

Echinacoside is a phenylethanoid glycoside that has been found in Echinacea and has diverse biological activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals (EC₅₀ = 6.6 μM in a cell-free assay). Echinacoside (10 μg/ml) inhibits hydrogen peroxide-induced production of reactive oxygen species (ROS) and apoptosis in PC12 cells. It reduces increases in plasma alanine aminotransferase (ALT), TNF-α, IL-1β, IL-16, and IL-10 levels and hepatocyte apoptosis induced by LPS/D-galactosamine in a mouse model of acute liver injury when administered at a dose of 60 mg/kg. Echinacoside (20 mg/kg per day for 15 days) prevents loss of dopaminergic neurons in the substantia nigra pars compacta and decreases in striatal dopamine and 3,4-dihydroxyphenylacetic acid (DOPAC) levels in a mouse model of MPTP-induced Parkinson''s disease. It also improves motor performance in the rotarod test in the same model.

Chemical Properties

White powder

Uses

Echinacoside Ethanolate is a caffeic acid glycoside, known for its neuroprotective, antiinflammatory and anti-oxidative activities. Also an anti[proliferative towards hypoxia influenced pulmonary artery smooth muscle cells.

Definition

ChEBI: Echinacoside is an oligosaccharide.

in vivo

Echinacoside (30-270 mg/kg body weight; p.o.; daily for 12 weeks) significantly reverses the increases of body weight, serum hydroxyproline (HOP) levels, and the decreases of uterus wet weight and bone mineral density (BMD) in In ovariectomized (OVX) rats^[3].

Animal Model:	Fifty-six aged 6 months female Sprague-Dawley rats (OVX rat model)^[3]
Dosage:	30, 90, 270 mg/kg body weight
Administration:	p.o.; daily for 12 weeks
Result:	The increases of body weight, serum hydroxyproline (HOP) levels, and the decreases of uterus wet weight and BMD were significantly reversed.

References

[1] FEDERICA PELLATI. Analysis of phenolic compounds and radical scavenging activity of Echinacea spp.[J]. Journal of pharmaceutical and biomedical analysis, 2004, 35 2: Pages 289-301. DOI: 10.1016/s0731-7085(03)00645-9
[2] RONG KUANG. Protective effects of echinacoside, one of the phenylethanoid glycosides, on H(2)O(2)-induced cytotoxicity in PC12 cells.[J]. Planta medica, 2009, 75 14: 1499-1504. DOI: 10.1055/s-0029-1185806
[3] XIUHUI LI. Echinacoside ameliorates D-galactosamine plus lipopolysaccharide-induced acute liver injury in mice via inhibition of apoptosis and inflammation.[J]. Scandinavian Journal of Gastroenterology, 2014, 49 8: 993-1000. DOI: 10.3109/00365521.2014.913190
[4] XINGCHAO GENG . Neuroprotective effects of echinacoside in the mouse MPTP model of Parkinson’s disease[J]. European journal of pharmacology, 2007, 564 1: Pages 66-74. DOI: 10.1016/j.ejphar.2007.01.084

ECHINACOSIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from ECHINACOSIDE manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Echinacoside 82854-37-3
Price: US $150.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 500kg
Release date: 2024-12-09

BINBO BIOLOGICAL CO.,LTD

Product: ECHINACOSIDE 82854-37-3
Price: US $0.00/kg
Min. Order: 1kg
Purity: 5%-80% 99%
Supply Ability: 1000 kg
Release date: 2024-11-25

Wuhan Han Sheng New Material Technology Co.，Ltd

Product: ECHINACOSIDE 20% DESERTLIVING CISTANCHE P.E. 82854-37-3
Price: US $31.74/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000kg
Release date: 2023-12-05

82854-37-3, ECHINACOSIDERelated Search:

Verbascoside Taxifolin METHYL CAFFEATE 6-O-BETA-D-GLUCOPYRANOSYL-D-GLUCOPYRANOSE 4-Hydroxybutyl acrylate [2-(1-Propoxyethoxy)ethyl]benzene ETHYL CAFFEATE Allyldiglycol 1-(2-(((1-ETHYLOXY)ETHYL)OXY)ETHYL)BENZENE Caffeic acid 2,3-DIHYDROXYPROPYL ACRYLATE ECHINACOSIDE Salidroside 3-Hydroxycinnamic acid 2-BUTOXYETHYL ACRYLATE HEXOXYETHYL ACRYLATE 2-(2-hydroxyethoxy)ethyl acrylate PHENYLETHYL BETA-D-GLUCOPYRANOSIDE

(1-3)-o-(beta-d-glucopyranosyl-(1-6))-,4-(3-(3,4-dihydroxyphenyl)-2-propenoat

2-(3,4-dihydroxyphenyl)ethylo-6-deoxy-alpha-l-mannopyranosyl-glucopyranosid

beta-d-e

ECHINACOSIDE

ECHINACOSIDE(AMERICAN HERBAL PHARMACOPOEIA)

ECHINACOSIDE 20% DESERTLIVING CISTANCHE P.E.

Cistanche tubulosa

Echinacoside/CH80711

Echinacoside/CH54339

ECHINACOSIDE(AHP)

Purpureaside C

Echinacoside, froM Cistanche deserticola Y.C.Ma

ECHINACOSIDE WITH HPLC

2-(3,4-Dihydroxyphenyl)ethyl 3-O-(6-deoxy-α-L-mannopyranosyl)-6-O-β-D-glucopyranosyl-4-O-[3-(3,4-dihydroxyphenyl)propenoyl]-β-D-glucopyranoside

[(2R,3R,4R,5R,6R)-6-[2-(3,4-Dihydroxyphenyl)ethoxy]-5-hydroxy-2-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate

Echinacoside, 98%, from Cistanche deserticola Y.C.Ma

Echicoside

Echinacoside [(2R,3R,4R,5R,6R)-6-[2-(3,4-Dihydroxyphenyl)ethoxy]-5-hydroxy-2-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)

Echinacoside Standard

β-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl O-6-deoxy-α-L-mannopyranosyl-(1→3)-O-[β-D-glucopyranosyl-(1→6)]-, 4-[3-(3,4-dihydroxyphenyl)-2-propenoate]

(2R,3R,4R,5R,6R)-6-(3,4-Dihydroxyphenethoxy)-5-hydroxy-2-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)-4-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-3-yl 3-(3,4-dihydroxyphenyl)acrylate

Cistanche tubulosa extrac

Cistanche Deserticola Extract Echinacoside

Echinacosidew

Echinacoside (P)

Echinacea Purpurea Cichoric Acid

Echinoside

Echinacoside, 10 mM in DMSO

82854-37-3

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

Sugars, Carbohydrates & Glucosides