4-(4-CHLORO-PHENYL)-5-METHYL-THIAZOL-2-YLAMINE

Product Name: 4-(4-CHLORO-PHENYL)-5-METHYL-THIAZOL-2-YLAMINE
CAS No.: 82632-77-7
Chemical Name: 4-(4-CHLORO-PHENYL)-5-METHYL-THIAZOL-2-YLAMINE
Synonyms: CHEMBRDG-BB 3007469;4-(4-chlorophenyl)-5-methyl-2-thiazolamine;4-(4-Chlorophenyl)-5-Methylthiazol-2-aMine;4-(4-CHLOROPHENY)-5-METHYLTHIAZOL-2-YLAMINE;2-Thiazolamine, 4-(4-chlorophenyl)-5-methyl-;4-(4-CHLORO-PHENYL)-5-METHYL-THIAZOL-2-YLAMINE;4-(4-chlorophenyl)-5-methyl-2-thiazol-3-idimine;4-(4-CHLOROPHENYL)-5-METHYL-1,3-THIAZOL-2-AMINE;4-(4-chlorophenyl)-5-methyl-1,3-thiazol-2-amine(SALTDATA: FREE)
CBNumber: CB7775907
Molecular Formula: C10H9ClN2S
Formula Weight: 224.71
MOL File: 82632-77-7.mol

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4-(4-CHLORO-PHENYL)-5-METHYL-THIAZOL-2-YLAMINE Property

Melting point:: 144-145℃ (hexane ethyl acetate )
Boiling point:: 376.6±27.0 °C(Predicted)
Density: 1.338±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: soluble in Methanol
form: powder to crystal
pka: 4.43±0.10(Predicted)
color: White to Yellow
CAS DataBase Reference: 82632-77-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 22-37/38-41
Safety Statements: 26-39
HS Code: 2934.10.2000
HazardClass: IRRITANT

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: JRD0109
Product name: 4-(4-Chlorophenyl)-5-methylthiazol-2-amine
Purity: Aldrich
Packaging: 1g
Price: $107
Updated: 2025/07/31

TCI Chemical

Product number: A3066
Product name: 2-Amino-4-(4-chlorophenyl)-5-methylthiazole
Purity: >98.0%(GC)
Packaging: 1g
Price: $77
Updated: 2025/07/31

TCI Chemical

Product number: A3066
Product name: 2-Amino-4-(4-chlorophenyl)-5-methylthiazole
Purity: >98.0%(GC)
Packaging: 5g
Price: $228
Updated: 2025/07/31

TRC

Product number: C350625
Product name: 4-(4-Chloro-phenyl)-5-methyl-thiazol-2-ylamine
Packaging: 100mg
Price: $45
Updated: 2021/12/16

TRC

Product number: C350625
Product name: 4-(4-Chloro-phenyl)-5-methyl-thiazol-2-ylamine
Packaging: 500mg
Price: $65
Updated: 2021/12/16

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4-(4-CHLORO-PHENYL)-5-METHYL-THIAZOL-2-YLAMINE Chemical Properties,Usage,Production

Synthesis

6285-05-8

17356-08-0

82632-77-7

GENERAL METHOD: Thiourea (0.04 mol) and iodine (0.02 mol) were ground homogeneously in a mortar and subsequently mixed with 4-chloropropiophenone (0.02 mol). The reaction mixture was heated in a water bath at 70°C with intermittent stirring for 8 hours. Upon completion of the reaction, the solid product was ground to a fine powder and washed with ether to remove unreacted 4-chloropropiophenone. Next, it was washed with 5% aqueous sodium thiosulfate to remove residual iodine and finally with distilled water. The crude product was dissolved in hot water and hot filtered to remove insoluble impurities. Ammonia was slowly added to the filtrate until 2-amino-4-(4'-chlorophenyl)-5-methyl-1,3-thiazole precipitated completely. The precipitate was collected and recrystallized with ethanol to give purified crystals of the target compound [9].

References

[1] Asian Journal of Chemistry, 2017, vol. 29, # 12, p. 2794 - 2798
[2] Journal of the Indian Chemical Society, 1960, vol. 37, p. 427 - 428
[3] Bioorganic and Medicinal Chemistry Letters, 2001, vol. 11, # 3, p. 313 - 317

4-(4-CHLORO-PHENYL)-5-METHYL-THIAZOL-2-YLAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(4-CHLORO-PHENYL)-5-METHYL-THIAZOL-2-YLAMINE Suppliers

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82632-77-7, 4-(4-CHLORO-PHENYL)-5-METHYL-THIAZOL-2-YLAMINERelated Search:

4-(2-Bromo-3-chloro-phenyl)-5- methyl-thiazol-2-ylamine 4-(3-CHLORO-PHENYL)-5-METHYL-THIAZOL-2-YLAMINE 5-Thiazoleacetic acid, 4-(4-chlorophenyl)-2-(((4-hydroxyphenyl)methyl) amino)-, methyl ester 4-(2,4-DICHLOROPHENYL)-5-METHYL-1,3-THIAZOL-2-AMINE HYDROBROMIDE 4-(4-CHLORO-PHENYL)-5-METHYL-THIAZOL-2-YLAMINE SALOR-INT L122041-1EA 5-Thiazoleacetic acid, 4-(4-chlorophenyl)-2-(((4-(dimethylamino)phenyl )methyl)amino)-, methyl ester ART-CHEM-BB B014642 5-Thiazoleacetic acid, 4-(4-chlorophenyl)-2-((phenylmethyl)amino)-, me thyl ester METHYL 2-(2-AMINO-4-(4-CHLOROPHENYL)THIAZOL-5-YL)ACETATE 4-(2,4-Dichloro-phenyl)-5- methyl-thiazol-2-ylamine SALOR-INT L120332-1EA 5-Thiazoleacetic acid, 2-(o-chlorobenzylamino)-4-(p-chlorophenyl)-, me thyl ester [4-(4-CHLORO-PHENYL)-5-METHYL-THIAZOL-2-YL]-HYDRAZINE 5-Thiazoleacetic acid, 4-(4-chlorophenyl)-2-(((2-hydroxyphenyl)methyl) amino)-, methyl ester

4-(4-chlorophenyl)-5-methyl-2-thiazolamine

4-(4-CHLOROPHENYL)-5-METHYL-1,3-THIAZOL-2-AMINE

4-(4-CHLORO-PHENYL)-5-METHYL-THIAZOL-2-YLAMINE

4-(4-CHLOROPHENY)-5-METHYLTHIAZOL-2-YLAMINE

4-(4-chlorophenyl)-5-methyl-1,3-thiazol-2-amine(SALTDATA: FREE)

4-(4-Chlorophenyl)-5-Methylthiazol-2-aMine

CHEMBRDG-BB 3007469

4-(4-chlorophenyl)-5-methyl-2-thiazol-3-idimine

2-Thiazolamine, 4-(4-chlorophenyl)-5-methyl-

82632-77-7