SQUALESTATIN

Product Name: SQUALESTATIN
CAS No.: 144541-82-2
Chemical Name: SQUALESTATIN
Synonyms: L-694,599;SQUALESTATIN;ZARAGOZIC ACID A SODIUM SALT;Zaragozic acid A trisodium salt
CBNumber: CB7779233
Molecular Formula: C35H47NaO14
Formula Weight: 714.74
MOL File: Mol file

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SQUALESTATIN Property

storage temp.: -20°C

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: Z2626
Product name: Zaragozic acid A trisodium salt
Purity: ≥95% (HPLC), microbial
Packaging: 5mg
Price: $624
Updated: 2024/03/01

TRC

Product number: Z150603
Product name: Zaragozic acid A trisodium salt
Packaging: 1mg
Price: $470
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: INB0001014
Product name: ZARAGOZIC ACID A TRISODIUM SALT
Purity: 95.00%
Packaging: 5MG
Price: $1036.09
Updated: 2021/12/16

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SQUALESTATIN Chemical Properties,Usage,Production

Uses

Zaragozic acid A trisodium salt is a potent inhibitor of squalene synthase.

Uses

Zaragozic acid A trisodium salt has been used as:

a component of serum-free medium for human embryonic kidney cells in a wound scratch assay to test its effect on wound healing
a farnesyl-diphosphate farnesyltransferase 1 (FDFT1) or squalene synthase inhibitor in stromal cells
a cholesterol synthesis inhibitor in T cells

Biochem/physiol Actions

Potent inhibitor, in vivo and in vitro, of mammalian, fungal and Saccharomyces cervisiae squalene synthase. Squalene synthase is the first committed enzyme in sterol synthesis, catalyzing the reductive condensation of farnesyl pyrophosphate to form squalene. As a squalene synthase inhibitor, zaragozic acid produces lower plasma cholesterol levels in primates. Treatment of rats with zaragozic acid A caused an increase in hepatic low density lipoprotein (LDL) receptor mRNA levels.

SQUALESTATIN Preparation Products And Raw materials

Raw materials

Preparation Products

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SQUALESTATIN Suppliers

China 4 India 2 Switzerland 1 United States 3 Global 10

Pharmaffiliates Analytics and Synthetics P. Ltd

Tel: --
Fax: --
Email: mktg@pharmaffiliates.com
Country: India
ProdList: 6739
Advantage: 58

144541-82-2, SQUALESTATINRelated Search:

Zaragozic acid A

SQUALESTATIN

L-694,599

Zaragozic acid A trisodium salt

ZARAGOZIC ACID A SODIUM SALT

144541-82-2