2-BROMO-4-PYRROLIDIN-1-YL-PYRIDINE
- Product Name
- 2-BROMO-4-PYRROLIDIN-1-YL-PYRIDINE
- CAS No.
- 230618-42-5
- Chemical Name
- 2-BROMO-4-PYRROLIDIN-1-YL-PYRIDINE
- Synonyms
- 2-Bromo-4-(pyrrolidino)pyridine;2-BROMO-4-PYRROLIDIN-1-YL-PYRIDINE;Pyridine, 2-bromo-4-(1-pyrrolidinyl)-
- CBNumber
- CB7805581
- Molecular Formula
- C9H11BrN2
- Formula Weight
- 227.1
- MOL File
- Mol file
2-BROMO-4-PYRROLIDIN-1-YL-PYRIDINE Property
- Melting point:
- 124 °C
- Boiling point:
- 335.5±27.0 °C(Predicted)
- Density
- 1.480±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 5.18±0.10(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 8299CR
- Product name
- 2-Bromo-4-(pyrrolidin-1-yl)pyridine
- Packaging
- 250mg
- Price
- $124
- Updated
- 2021/12/16
- Product number
- 8299CR
- Product name
- 2-Bromo-4-(pyrrolidin-1-yl)pyridine
- Packaging
- 5g
- Price
- $608
- Updated
- 2021/12/16
- Product number
- 104882
- Product name
- 2-Bromo-4-(pyrrolidin-1-yl)pyridine
- Packaging
- 1g
- Price
- $1143
- Updated
- 2021/12/16
- Product number
- A124802
- Product name
- 2-Bromo-4-(pyrrolidin-1-yl)pyridine
- Purity
- 97%
- Packaging
- 100mg
- Price
- $32
- Updated
- 2021/12/16
- Product number
- A124802
- Product name
- 2-Bromo-4-(pyrrolidin-1-yl)pyridine
- Purity
- 97%
- Packaging
- 250mg
- Price
- $63
- Updated
- 2021/12/16
2-BROMO-4-PYRROLIDIN-1-YL-PYRIDINE Chemical Properties,Usage,Production
Synthesis
123-75-1
58530-53-3
230618-42-5
2,4-dibromopyridine (300 mg, 0.94 mmol) and pyrrolidine (335 mg, 4.7 mmol) were mixed in ethanol and reacted at 70 °C overnight. After completion of the reaction, the reaction mixture was concentrated under vacuum and the resulting residue was purified by ISCO? column chromatography using a silica column with 0-70% ethyl acetate/pentane as eluent. The target product 2-bromo-4-(pyrrolidin-1-yl)pyridine (208 mg, 0.91 mmol, 97% yield) was finally obtained. The structure of the product was confirmed by 1H-NMR (CDCl3, 400 MHz): δ 2.0 (m, 4H), 3.3 (m, 4H), 6.3 (m, 1H), 6.6 (s, 1H), 7.9 (d, 1H).LRMS m/z (APCI) 227 [MH]+.
References
[1] Patent: WO2007/57775, 2007, A1. Location in patent: Page/Page column 160
2-BROMO-4-PYRROLIDIN-1-YL-PYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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