MYF-01-37

Product Name: MYF-01-37
CAS No.: 2416417-65-5
Chemical Name: MYF-01-37
Synonyms: MYF-01-37;MYF-01-37 ，S8950;MYF-01-37, 10 mM in DMSO;1-[3-Methyl-3-[3-(trifluoromethyl)anilino]pyrrolidin-1-yl]prop-2-en-1-one;1-(3-Methyl-3-((3-(trifluoromethyl)phenyl)amino)pyrrolidin-1-yl)prop-2-en-1-one;2-Propen-1-one, 1-[3-methyl-3-[[3-(trifluoromethyl)phenyl]amino]-1-pyrrolidinyl]-;Cys380,MYF 01 37,inhibit,Inhibitor,MYF0137,YAP/TEAD,Yes-associated protein,HEK293T,YAP
CBNumber: CB78066458
Molecular Formula: C15H17F3N2O
Formula Weight: 298.3
MOL File: 2416417-65-5.mol

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MYF-01-37 Property

Boiling point:: 421.7±45.0 °C(Predicted)
Density: 1.245±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : 250 mg/mL (838.08 mM; Need ultrasonic)
pka: 5.17±0.20(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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MYF-01-37 Chemical Properties,Usage,Production

Uses

MYF-01-37 is a covalent TEAD inhibitor targeting Cys380. MYF-01-37 has a reversible inhibition on YAP/TEAD interaction[1].

IC 50

YAP/TAZ-TEAD

References

[1] Kari J Kurppa, et al. Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway. Cancer Cell. 2020 Jan 13;37(1):104-122.e12. DOI:10.1016/j.ccell.2019.12.006

MYF-01-37 Preparation Products And Raw materials

Raw materials

Preparation Products

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MYF-01-37 Suppliers

China 45 United States 3 Global 48

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2416417-65-5, MYF-01-37Related Search:

MYF-01-37

1-[3-Methyl-3-[3-(trifluoromethyl)anilino]pyrrolidin-1-yl]prop-2-en-1-one

Cys380,MYF 01 37,inhibit,Inhibitor,MYF0137,YAP/TEAD,Yes-associated protein,HEK293T,YAP

2-Propen-1-one, 1-[3-methyl-3-[[3-(trifluoromethyl)phenyl]amino]-1-pyrrolidinyl]-

1-(3-Methyl-3-((3-(trifluoromethyl)phenyl)amino)pyrrolidin-1-yl)prop-2-en-1-one

MYF-01-37, 10 mM in DMSO

MYF-01-37 ，S8950

2416417-65-5