Fluorinated VHL Spy Molecule 4

Product Name: Fluorinated VHL Spy Molecule 4
CAS No.: 2290526-31-5
Chemical Name: Fluorinated VHL Spy Molecule 4
Synonyms: Fluorinated VHL Spy Molecule 4;(2S,4R)-N-(4-bromobenzyl)-4-hydroxy-1-(3,3,3-trifluoropropanoyl)pyrrolidine-2-carboxamide;(2S,4R)-N-[(4-bromophenyl)methyl]-4-hydroxy-1-(3,3,3-trifluoropropanoyl)pyrrolidine-2-carboxamide;2-Pyrrolidinecarboxamide, N-[(4-bromophenyl)methyl]-4-hydroxy-1-(3,3,3-trifluoro-1-oxopropyl)-, (2S,4R)-
CBNumber: CB78362275
Molecular Formula: C15H16BrF3N2O3
Formula Weight: 409.2
MOL File: 2290526-31-5.mol

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Fluorinated VHL Spy Molecule 4 Property

Boiling point:: 595.3±50.0 °C(Predicted)
Density: 1.586±0.06 g/cm3(Predicted)
pka: 14.02±0.40(Predicted)
form: powder

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 909459
Product name: Fluorinated VHL Spy Molecule 4
Purity: ≥98%
Packaging: 10mg
Price: $120
Updated: 2023/06/20

Sigma-Aldrich

Product number: 909459
Product name: Fluorinated VHL Spy Molecule 4
Purity: ≥98%
Packaging: 100mg
Price: $308
Updated: 2023/06/20

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Fluorinated VHL Spy Molecule 4 Chemical Properties,Usage,Production

Uses

Fluorinated VHL Spy Molecule 4 can be used for the discovery of new von Hippel-Lindau (VHL) binders. Based on VH032 (cat# 901490), this reporter was designed in the lab of Alessio Ciulli to bind the hydroxyproline (Hyp) recognition site of VHL. When used in competition ligand-observed 19F NMR screening experiments, its displacement indicates binding by another molecule. Additional Fluorinated VHL Spy Molecules are available as listings 909416, 909432, and 909440.
The E3 ligase VHL is of growing interest for targeted protein degradation, and these spy molecules will facilitate the identification of novel VHL ligands and VHL-based degraders.

Fluorinated VHL Spy Molecule 4 Preparation Products And Raw materials

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Fluorinated VHL Spy Molecule 4 Suppliers

China 6 United States 1 Global 7

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2290526-31-5, Fluorinated VHL Spy Molecule 4Related Search:

Fluorinated VHL Spy Molecule 4

2-Pyrrolidinecarboxamide, N-[(4-bromophenyl)methyl]-4-hydroxy-1-(3,3,3-trifluoro-1-oxopropyl)-, (2S,4R)-

(2S,4R)-N-(4-bromobenzyl)-4-hydroxy-1-(3,3,3-trifluoropropanoyl)pyrrolidine-2-carboxamide

(2S,4R)-N-[(4-bromophenyl)methyl]-4-hydroxy-1-(3,3,3-trifluoropropanoyl)pyrrolidine-2-carboxamide

2290526-31-5