ChemicalBook > CAS DataBase List > Hydrazinecarbothioamide, 2-[1-(2-thienyl)ethylidene]-, (2Z)-
Hydrazinecarbothioamide, 2-[1-(2-thienyl)ethylidene]-, (2Z)-
- Product Name
- Hydrazinecarbothioamide, 2-[1-(2-thienyl)ethylidene]-, (2Z)-
- CAS No.
- 433212-75-0
- Chemical Name
- Hydrazinecarbothioamide, 2-[1-(2-thienyl)ethylidene]-, (2Z)-
- Synonyms
- SSAA09E1;SSAA09E1 [(Z)-1-Thiophen-2-ylethylideneamino]thiourea;(2Z)-2-[1-(2-thienyl)ethylidene]-hydrazinecarbothioamide;Hydrazinecarbothioamide, 2-[1-(2-thienyl)ethylidene]-, (2Z)-
- CBNumber
- CB78379772
- Molecular Formula
- C7H9N3S2
- Formula Weight
- 199.3
- MOL File
- 433212-75-0.mol
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Hydrazinecarbothioamide, 2-[1-(2-thienyl)ethylidene]-, (2Z)- Property
- Boiling point:
- 333.0±34.0 °C(Predicted)
- Density
- 1.37±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Ethanol: soluble
- form
- A crystalline solid
- pka
- 11.50±0.70(Predicted)
- color
- White to off-white
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Hydrazinecarbothioamide, 2-[1-(2-thienyl)ethylidene]-, (2Z)- Chemical Properties,Usage,Production
Biological Activity
SSAA09E1 is an inhibitor of severe acute respiratory syndrome coronavirus (SARS-CoV) viral entry.1 It reduces infection of HEK293T cells transiently transfected with angiotensin-converting enzyme 2 (ACE2) by an HIV-based virus system pseudotyped with SARS-CoV surface glycoprotein (EC50 = 6.7 μM). SSAA09E1 also inhibits the proteolytic activity of cathepsin L (IC50 = 5.33 μM) but not cathepsin B when used at a concentration of 20 μM.
References
1.()
Hydrazinecarbothioamide, 2-[1-(2-thienyl)ethylidene]-, (2Z)- Preparation Products And Raw materials
Raw materials
Preparation Products
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