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AMBUPHYLLINE

Product Name
AMBUPHYLLINE
CAS No.
5634-34-4
Chemical Name
AMBUPHYLLINE
Synonyms
Bufylline;Busylline;AMBUPHYLLINE;THEOPHYLLINE (AMBUPHYLLINE);Theophylline-?aminoisobutanol;THEOPHYLLINE-2-AMINOISOBUTANOL;1,3-Dimethyl-7H-purine-2,6-dione 2-amin;2-amino-2-methylpropan-1-ol,1,3-dimethyl-7H-purine-2,6-dione;1,3-Dimethyl-7H-purine-2,6-dione 2-amino-2-methylpropan-1-ol;3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione, compound with 2-amino-2-methylpropan-1-ol (1:1)
CBNumber
CB7838718
Molecular Formula
C11H18N5O3
Formula Weight
268.29232
MOL File
5634-34-4.mol
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AMBUPHYLLINE Property

Melting point:
254-256°
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Safety

Toxicity
LD50 i.v. in rabbits: 163 mg/kg; orally in mice: 600 mg/kg, (Thompson, Warren)
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Hazard and Precautionary Statements (GHS)

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AMBUPHYLLINE Chemical Properties,Usage,Production

Originator

Butaphyllamine,Merrell Dow,US,1944

Uses

Diuretic; relaxant (smooth muscle).

Manufacturing Process

Equimolecular proportions of theophylline and 2-amino-2-methyl-1-propanol are dissolved in water and the water is evaporated until crystallization is almost complete. The crystals are filtered off and dried. The product has a melting point of 254-256°C, softening at 245°C. It has a water solubility of about 55%. It may be compounded in the form of tablets, for oral administration, or may be prepared in solution for distribution in ampoules. For the manufacture of solutions for packaging in ampoules, it is more convenient to simply dissolve the theophylline and the butanolamine in water, without going through the intermediate step of separating the crystalline salt.

brand name

Butaphyllamine (Marion Merrell Dow).

Therapeutic Function

Diuretic, Smooth muscle relaxant

AMBUPHYLLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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AMBUPHYLLINE Suppliers

Dr. J. Pharmachem (India)
Tel
+91 20 24332987
Fax
+91 20 24332137
Email
info@jpharmachem.com
Country
India
ProdList
97
Advantage
55
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49391
Advantage
58
TCI (Shanghai) Chemical Trading Co., Ltd.
Tel
021-61109150
Fax
021-61105897
Email
sales@tcisct.com
Country
China
ProdList
31163
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24018
Advantage
58
Shaanxi Dideu Newmaterial Co., Ltd.
Tel
029-63373950 15353716720
Email
1052@dideu.com
Country
China
ProdList
10011
Advantage
58

5634-34-4, AMBUPHYLLINERelated Search:


  • AMBUPHYLLINE
  • THEOPHYLLINE-2-AMINOISOBUTANOL
  • Theophylline-?aminoisobutanol
  • 3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione, compound with 2-amino-2-methylpropan-1-ol (1:1)
  • Busylline
  • Bufylline
  • THEOPHYLLINE (AMBUPHYLLINE)
  • 1,3-Dimethyl-7H-purine-2,6-dione 2-amino-2-methylpropan-1-ol
  • 1,3-Dimethyl-7H-purine-2,6-dione 2-amin
  • 2-amino-2-methylpropan-1-ol,1,3-dimethyl-7H-purine-2,6-dione
  • 5634-34-4
  • C11H19N5O3